HitPredict

Interactor 1: ROA2 (P22626)
Heterogeneous nuclear ribonucleoproteins A2/B1 (hnRNP A2/B1)
Gene: HNRNPA2B1

Interactor 2: RC3H1 (Q5TC82)
Roquin-1 (Roquin) (EC 2.3.2.27) (RING finger and C3H zinc finger protein 1) (RING finger and CCCH-type zinc finger domain-containing protein 1) (RING finger protein 198)
Gene: RC3H1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	26170170, 30209976
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0003730 - mRNA 3'-UTR binding GO:0035198 - miRNA binding
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 353 Hs			1 1133
+	Hs
		162068 HNRDL_HUMAN (12-292): 9.81e-66: 215: 33.45		RC3H1_HUMAN (1-1133): 0: 1909: 100.00
+	Hs
		201679 MSI1H_HUMAN (3-341): 3.78e-60: 199: 28.77		RC3H1_HUMAN (1-1133): 0: 1909: 100.00
+	Hs
		1136221 MSI2H_HUMAN (1-341): 1.1e-55: 186: 27.57		RC3H1_HUMAN (1-1133): 0: 1909: 100.00
+	Hs
		1031360 PABP4_HUMAN (19-200): 1.59e-38: 146: 19.67		RC3H1_HUMAN (1-1133): 0: 1909: 100.00
+	Hs
		516550 PABP1_HUMAN (12-200): 2.75e-37: 143: 18.95		RC3H1_HUMAN (1-1133): 0: 1909: 100.00
+	Hs
		1048096 HNRPD_HUMAN (22-191): 3.34e-37: 138: 41.77		RC3H1_HUMAN (1-1133): 0: 1909: 100.00
+	Hs
		852082 ROA3_HUMAN (3-103): 2.78e-17: 84: 33.66		RC3H1_HUMAN (1-1133): 0: 1909: 100.00
+	Hs
		453413 ROA1_HUMAN (3-96): 6.48e-16: 79.8: 31.92		RC3H1_HUMAN (1-1133): 0: 1909: 100.00
+	Hs
		162161 HNRDL_HUMAN (12-292): 9.81e-66: 215: 33.45		RC3H2_HUMAN (1-1107): 0: 1494: 51.72
+	Hs
		610054 ROA2_HUMAN (1-353): 9.07e-61: 200: 100.00		RC3H2_HUMAN (1-1107): 0: 1494: 51.72
+	Hs
		201713 MSI1H_HUMAN (3-341): 3.78e-60: 199: 28.77		RC3H2_HUMAN (1-1107): 0: 1494: 51.72
+	Hs
		1288220 MSI2H_HUMAN (1-341): 1.1e-55: 186: 27.57		RC3H2_HUMAN (1-1107): 0: 1494: 51.72
+	Hs
		1031467 PABP4_HUMAN (19-200): 1.59e-38: 146: 19.67		RC3H2_HUMAN (1-1107): 0: 1494: 51.72
+	Hs
		516698 PABP1_HUMAN (12-200): 2.75e-37: 143: 18.95		RC3H2_HUMAN (1-1107): 0: 1494: 51.72
+	Hs
		1048234 HNRPD_HUMAN (22-191): 3.34e-37: 138: 41.77		RC3H2_HUMAN (1-1107): 0: 1494: 51.72
+	Hs
		453620 ROA1_HUMAN (3-96): 6.48e-16: 79.8: 31.92		RC3H2_HUMAN (1-1107): 0: 1494: 51.72