Protein: FLI1
Friend leukemia integration 1 transcription factor (Proto-oncogene Fli-1) (Transcription factor ERGB)

Gene: FLI1
Organism: Homo sapiens
Interactions: 59
UniProt ID: Q01543

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000976 - transcription cis-regulatory region binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

540842

ERG
Transcriptional regulator ERG

2

18

Small-scale

0.754

High

832971

ETV6
Transcription factor ETV6

1

18

Small-scale

0.740

High

590404

GATA1
Erythroid transcription factor

3

9

Small-scale

0.683

High

622439

ELK1
ETS domain-containing protein Elk-1

1

19

Small-scale

0.647

High

662213

PAX7
Paired box protein Pax-7

1

8

High-throughput

0.618

High

846900

ETV4
ETS translocation variant 4

1

17

High-throughput

0.618

High

938432

PAX9
Paired box protein Pax-9

1

2

High-throughput

0.618

High

297794

PIAS2
E3 SUMO-protein ligase PIAS2

1

14

Small-scale

0.586

High

1030971

KAT2B
Histone acetyltransferase KAT2B

2

20

Small-scale

0.584

High

325207

SOX30
Transcription factor SOX-30

1

20

High-throughput

0.573

High

941402

CTBP2
C-terminal-binding protein 2

1

2

High-throughput

0.573

High

1030964

SIAH1
E3 ubiquitin-protein ligase SIAH1

1

1

High-throughput

0.573

High

1014477

SMAD3
Mothers against decapentaplegic homolog 3

1

4

High-throughput

0.568

High

1030955

KPCD
Protein kinase C delta type

1

2

Small-scale

0.561

High

1030958

KLF1
Krueppel-like factor 1

1

20

Small-scale

0.561

High

181880

SMAD9
Mothers against decapentaplegic homolog 9

1

4

High-throughput

0.508

High

297575

PIAS1
E3 SUMO-protein ligase PIAS1

1

14

Small-scale

0.501

High

549310

SRF
Serum response factor

1

6

Small-scale

0.501

High

799002

BRCA1
Breast cancer type 1 susceptibility protein

1

8

Small-scale

0.501

High

993501

UBC9
SUMO-conjugating enzyme UBC9

1

9

Small-scale

0.481

High

142943

NFIB
Nuclear factor 1 B-type

1

20

High-throughput

0.479

High

154670

ARI1A
AT-rich interactive domain-containing protein 1A

1

20

Small-scale

0.479

High

209983

CRX
Cone-rod homeobox protein

1

12

High-throughput

0.479

High

239938

SOX15
Transcription factor SOX-15

1

17

High-throughput

0.479

High

337582

FMNL1
Formin-like protein 1

1

3

Small-scale

0.479

High

355197

ACL6A
Actin-like protein 6A

1

4

Small-scale

0.479

High

413646

P53
Cellular tumor antigen p53

1

5

Small-scale

0.479

High

473920

NFIC
Nuclear factor 1 C-type

1

20

High-throughput

0.479

High

538386

EGR2
E3 SUMO-protein ligase EGR2

1

9

High-throughput

0.479

High

659212

SP100
Nuclear autoantigen Sp-100

1

17

Small-scale

0.479

High

775019

FUS
RNA-binding protein FUS

1

8

Small-scale

0.479

High

872212

SOX2
Transcription factor SOX-2

1

19

High-throughput

0.479

High

886766

CEBPA
CCAAT/enhancer-binding protein alpha

1

9

High-throughput

0.479

High

903133

SMCA2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2

1

19

Small-scale

0.479

High

903323

SMCA4
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4

1

20

Small-scale

0.479

High

942427

GSC
Homeobox protein goosecoid

1

18

High-throughput

0.479

High

998222

H31
Histone H3.1

1

12

High-throughput

0.479

High

1016781

H33
Histone H3.3

1

12

High-throughput

0.479

High

1030953

EWS
RNA-binding protein EWS

1

7

Small-scale

0.479

High

1030954

IRF8
Interferon regulatory factor 8

1

3

High-throughput

0.479

High

1030956

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

1

3

Small-scale

0.479

High

1030957

NFIA
Nuclear factor 1 A-type

1

20

High-throughput

0.479

High

1030959

NFIX
Nuclear factor 1 X-type

1

20

High-throughput

0.479

High

1030960

SSXT
Protein SSXT

1

20

Small-scale

0.479

High

1030961

ARID2
AT-rich interactive domain-containing protein 2

1

20

Small-scale

0.479

High

1030962

SMRD3
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3

1

12

Small-scale

0.479

High

1030963

PB1
Protein polybromo-1

1

20

Small-scale

0.479

High

1030965

ARI1B
AT-rich interactive domain-containing protein 1B

1

20

Small-scale

0.479

High

1030966

SMRC2
SWI/SNF complex subunit SMARCC2

1

20

Small-scale

0.479

High

1030967

SP7
Transcription factor Sp7

1

20

High-throughput

0.479

High

1030968

PHF10
PHD finger protein 10

1

20

Small-scale

0.479

High

1030969

REQU
Zinc finger protein ubi-d4

1

20

Small-scale

0.479

High

1030970

RBP56
TATA-binding protein-associated factor 2N

1

8

Small-scale

0.479

High

1030972

SMRC1
SWI/SNF complex subunit SMARCC1

1

19

Small-scale

0.479

High

1030973

SMRD2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2

1

18

Small-scale

0.479

High

1030974

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

1

9

Small-scale

0.479

High

1030975

SMCE1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1

1

12

Small-scale

0.479

High

1030976

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

1

12

Small-scale

0.479

High

760750

CD68
Macrosialin

1

1

Small-scale

0.470

High


Service provided by Combinatics, Japan

Last updated: 11Aug2025