HitPredict

Interactor 1: VGFR1 (P17948)
Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like tyrosine kinase 1) (FLT-1) (Tyrosine-protein kinase FRT) (Tyrosine-protein kinase receptor FLT) (FLT) (Vascular permeability factor receptor)
Gene: FLT1

Interactor 2: VGFR1 (P17948)
Vascular endothelial growth factor receptor 1 (VEGFR-1) (EC 2.7.10.1) (Fms-like tyrosine kinase 1) (FLT-1) (Tyrosine-protein kinase FRT) (Tyrosine-protein kinase receptor FLT) (FLT) (Vascular permeability factor receptor)
Gene: FLT1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.692

The method score is based on:

Property Details
Experiments 7657594
Identification Methods enzymatic study, protein kinase assay
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains I-set~I-set, I-set~ig, I-set~Ig_3, I-set~VEGFR-1-like_5th, ig~ig, Ig_3~ig, VEGFR-1-like_Ig-like~ig, Ig_3~Ig_3, Ig_3~VEGFR-1-like_5th, VEGFR-1-like_5th~VEGFR-1-like_5th, PK_Tyr_Ser-Thr~PK_Tyr_Ser-Thr, VEGFR-1-like_Ig-like~VEGFR-1-like_Ig-like, VEGFR-1-like_Ig-like~VEGFR1-3_N_Ig-like, VEGFR-2_TMD~VEGFR-2_TMD
Common GO terms GO:0002040 - sprouting angiogenesis
GO:0002548 - monocyte chemotaxis
GO:0004714 - transmembrane receptor protein tyrosine kinase activity
GO:0005021 - vascular endothelial growth factor receptor activity
GO:0005524 - ATP binding
and 27 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 1338
Hs

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Last updated: 11Aug2025