HitPredict

Interactor 1: MLR (P18432)
Myosin regulatory light chain 2 (MLC-2)
Gene: Mlc2

Interactor 2: TNNC1 (P47947)
Troponin C, isoform 1
Gene: TpnC41C

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	22036573, 38944040
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	EF-hand_6~EF-hand_7
Common GO terms	GO:0005509 - calcium ion binding GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 222 Dm			1 154
+	Dm
		614559 MLR_DROME (1-222): 2.65e-62: 195: 100.00		TNNC3_DROME (1-151): 3.1e-51: 162: 63.58
+	Dm
		614558 MLR_DROME (1-222): 2.65e-62: 195: 100.00		TNNC2_DROME (1-151): 2.22e-50: 160: 64.24
+	Dm
		614576 MLR_DROME (1-222): 2.65e-62: 195: 100.00		Q7K860_DROME (4-151): 1.2e-46: 150: 59.73
+	Dm
		614617 MLR_DROME (1-222): 2.65e-62: 195: 100.00		Q9VMT2_DROME (8-151): 6.57e-40: 133: 56.25
+	At
		1182290 CDPK4_ARATH (1-214): 2.88e-66: 214: 20.91		CDPK4_ARATH (16-148): 8.26e-12: 63.7: 18.84
+	At
		1183276 CDPKB_ARATH (1-214): 2.84e-65: 211: 21.36		CDPKB_ARATH (71-148): 1.54e-11: 62.9: 29.49
+	At
		1183297 CDPKO_ARATH (1-213): 2.86e-49: 170: 18.02		CDPKB_ARATH (71-148): 1.54e-11: 62.9: 29.49
+	At
		200310 CDPKU_ARATH (138-220): 3.15e-11: 63.8: 18.82		CML8_ARATH (5-153): 1.73e-24: 94: 41.61
+	At
		200257 CDPK3_ARATH (135-220): 1.06e-10: 62.3: 20.46		CML8_ARATH (5-153): 1.73e-24: 94: 41.61
+	At
		668867 CDPKU_ARATH (138-220): 3.15e-11: 63.8: 18.82		CML12_ARATH (1-149): 5.22e-21: 88.6: 34.57
+	Hs
		516385 CALM2_HUMAN (140-220): 7.51e-16: 73.5: 22.89		CALL3_HUMAN (77-151): 1.2e-12: 63.3: 44.00
+	Hs
		516458 CALM3_HUMAN (15-139): 3.24e-14: 69.2: 17.56		CALM3_HUMAN (6-76): 9.82e-14: 66: 33.80
+	At
		515553 CDPKA_ARATH (85-220): 2.5e-12: 67.3: 15.39		CALM4_ARATH (1-76): 1.95e-13: 65.2: 32.47
+	Hs
		516311 CALM1_HUMAN (15-139): 3.24e-14: 69.2: 17.56		CALL3_HUMAN (77-151): 1.2e-12: 63.3: 44.00
+	At
		1057375 CDPK1_ARATH (132-220): 1.15e-10: 62.3: 19.78		CDPK1_ARATH (66-148): 2.98e-13: 67.9: 30.12
+	At
		515564 CDPKU_ARATH (138-220): 3.15e-11: 63.8: 18.82		CALM4_ARATH (1-76): 1.95e-13: 65.2: 32.47
+	At
		1043103 CDPKU_ARATH (138-220): 3.15e-11: 63.8: 18.82		CALM6_ARATH (6-76): 3.21e-13: 64.8: 33.80
+	At
		947591 CDPKU_ARATH (138-220): 3.15e-11: 63.8: 18.82		CALM7_ARATH (6-76): 2.68e-13: 64.8: 33.80
+	Gm
		1284629 Q84P28_SOYBN (135-220): 4.09e-11: 63.4: 21.59		Q84P28_SOYBN (71-148): 3.11e-12: 64.8: 29.49
+	At
		515475 CDPK3_ARATH (135-220): 1.06e-10: 62.3: 20.46		CALM4_ARATH (1-76): 1.95e-13: 65.2: 32.47