HitPredict

Interactor 1: SEC18 (P18759)
Vesicular-fusion protein SEC18
Gene: SEC18

Interactor 2: RPN5 (Q12250)
26S proteasome regulatory subunit RPN5 (Proteasome non-ATPase subunit 5)
Gene: RPN5

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.80	0.694

Property	Details
Experiments	16554755, 22940862
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	AAA~PSMD12-CSN4_N, AAA_lid_3~PSMD12-CSN4_N
Common GO terms	-
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 758 Sc			1 445
+	Sc
		616466 SEC18_YEAST (1-758): 1.14e-179: 534: 100.00		RPN6_YEAST (8-434): 2.77e-73: 238: 10.58
+	Hs
		91844 C9JUP7_HUMAN (173-545): 7.37e-73: 254: 27.66		PSD12_HUMAN (7-443): 3.18e-131: 387: 40.45
+	Hs
		128188 TERA_HUMAN (173-545): 4.15e-72: 252: 27.66		PSD12_HUMAN (7-443): 3.18e-131: 387: 40.45
+	Sc
		680164 CDC48_YEAST (59-538): 1e-73: 257: 22.94		RPN5_YEAST (1-445): 1.92e-114: 344: 100.00
+	Hs
		127913 TERA_HUMAN (173-545): 4.15e-72: 252: 27.66		PSD11_HUMAN (20-435): 2.55e-93: 289: 12.68
+	Hs
		935069 TERA_HUMAN (173-545): 4.15e-72: 252: 27.66		CSN4_HUMAN (69-435): 2.69e-88: 276: 18.37
+	Sc
		680178 CDC48_YEAST (59-538): 1e-73: 257: 22.94		RPN6_YEAST (8-434): 2.77e-73: 238: 10.58