HitPredict

Interactor 1: COF1 (P23528)
Cofilin-1 (18 kDa phosphoprotein) (p18) (Cofilin, non-muscle isoform)
Gene: CFL1

Interactor 2: ATX1 (P54253)
Ataxin-1 (Spinocerebellar ataxia type 1 protein)
Gene: ATXN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.639

Property	Details
Experiments	16713569, 32814053
Identification Methods	two hybrid, affinity chromatography technology, validated two hybrid, two hybrid array, two hybrid pooling approach, pull down
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016363 - nuclear matrix
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 166 Hs			1 815
+	Mm
		869301 DEST_MOUSE (1-166): 1.45e-70: 211: 70.48		ATX1_MOUSE (1-815): 0: 1271: 86.89
+	Mm
		869155 TWF1_MOUSE (3-157): 1.15e-33: 123: 20.89		ATX1_MOUSE (1-815): 0: 1271: 86.89