HitPredict

Interactor 1: CDC42 (P19073)
Cell division control protein 42 (EC 3.6.5.2) (Suppressor of RHO3 protein 2)
Gene: CDC42

Interactor 2: KES1 (P35844)
Oxysterol-binding protein homolog 4 (Bypass SECl4 recessive protein 3) (KRE11-1 suppressor protein 1) (Protein KES1) (Oxysterol-binding protein-related protein 4) (ORP 4) (OSBP-related protein 4)
Gene: KES1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	21819498
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006897 - endocytosis
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 191 Sc			1 434
+	Hs
		988680 RAC1_HUMAN (1-191): 5.19e-82: 243: 68.75		OSBL8_HUMAN (4-399): 4.04e-132: 403: 23.52
+	Hs
		1015750 RHOG_HUMAN (1-191): 9.03e-81: 240: 58.64		OSBL8_HUMAN (4-399): 4.04e-132: 403: 23.52
+	Hs
		1419785 RHOJ_HUMAN (2-189): 4.78e-79: 236: 59.04		OSBL8_HUMAN (4-399): 4.04e-132: 403: 23.52
+	Hs
		955557 CDC42_HUMAN (1-191): 1.47e-79: 236: 80.11		OSBL8_HUMAN (4-399): 4.04e-132: 403: 23.52
+	Hs
		581270 RAC2_HUMAN (1-191): 2.85e-78: 233: 67.71		OSBL8_HUMAN (4-399): 4.04e-132: 403: 23.52
+	Hs
		962447 RHOA_HUMAN (5-191): 3.86e-77: 230: 51.34		OSBL8_HUMAN (4-399): 4.04e-132: 403: 23.52
+	Hs
		988707 RAC1_HUMAN (1-191): 5.19e-82: 243: 68.75		OSBL3_HUMAN (5-383): 4.1e-125: 385: 20.20
+	Hs
		1015785 RHOG_HUMAN (1-191): 9.03e-81: 240: 58.64		OSBL3_HUMAN (5-383): 4.1e-125: 385: 20.20
+	Hs
		1433505 RHOJ_HUMAN (2-189): 4.78e-79: 236: 59.04		OSBL3_HUMAN (5-383): 4.1e-125: 385: 20.20
+	Hs
		581290 RAC2_HUMAN (1-191): 2.85e-78: 233: 67.71		OSBL3_HUMAN (5-383): 4.1e-125: 385: 20.20
+	Hs
		581247 RAC2_HUMAN (1-191): 2.85e-78: 233: 67.71		OSBL9_HUMAN (2-373): 4.27e-125: 381: 27.44
+	Hs
		988673 RAC1_HUMAN (1-191): 5.19e-82: 243: 68.75		OSB10_HUMAN (3-373): 1.46e-119: 367: 22.36
+	Hs
		1015735 RHOG_HUMAN (1-191): 9.03e-81: 240: 58.64		OSB10_HUMAN (3-373): 1.46e-119: 367: 22.36
+	Hs
		955546 CDC42_HUMAN (1-191): 1.47e-79: 236: 80.11		OSB10_HUMAN (3-373): 1.46e-119: 367: 22.36
+	Hs
		988672 RAC1_HUMAN (1-191): 5.19e-82: 243: 68.75		OSB11_HUMAN (2-370): 1.23e-116: 359: 21.89
+	Hs
		581265 RAC2_HUMAN (1-191): 2.85e-78: 233: 67.71		OSB10_HUMAN (3-373): 1.46e-119: 367: 22.36
+	Hs
		1015734 RHOG_HUMAN (1-191): 9.03e-81: 240: 58.64		OSB11_HUMAN (2-370): 1.23e-116: 359: 21.89
+	Hs
		962440 RHOA_HUMAN (5-191): 3.86e-77: 230: 51.34		OSB10_HUMAN (3-373): 1.46e-119: 367: 22.36
+	Hs
		581264 RAC2_HUMAN (1-191): 2.85e-78: 233: 67.71		OSB11_HUMAN (2-370): 1.23e-116: 359: 21.89
+	Hs
		962439 RHOA_HUMAN (5-191): 3.86e-77: 230: 51.34		OSB11_HUMAN (2-370): 1.23e-116: 359: 21.89