HitPredict

Interactor 1: RAC2 (P15153)
Ras-related C3 botulinum toxin substrate 2 (EC 3.6.5.2) (GX) (Small G protein) (p21-Rac2)
Gene: RAC2

Interactor 2: OSBL9 (Q96SU4)
Oxysterol-binding protein-related protein 9 (ORP-9) (OSBP-related protein 9)
Gene: OSBPL9

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~Ras
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Hs			1 736
+	Hs
		601415 RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03		OSBL9_HUMAN (1-736): 0: 730: 100.00
+	Hs
		988673 RAC1_HUMAN (1-192): 3.43e-86: 253: 92.19		OSB10_HUMAN (3-730): 0: 540: 36.02
+	Hs
		581265 RAC2_HUMAN (1-192): 1.14e-83: 247: 100.00		OSB10_HUMAN (3-730): 0: 540: 36.02
+	Hs
		988672 RAC1_HUMAN (1-192): 3.43e-86: 253: 92.19		OSB11_HUMAN (7-729): 3.9e-180: 534: 37.08
+	Hs
		581264 RAC2_HUMAN (1-192): 1.14e-83: 247: 100.00		OSB11_HUMAN (7-729): 3.9e-180: 534: 37.08
+	Hs
		601427 RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03		OSB11_HUMAN (7-729): 3.9e-180: 534: 37.08
+	Hs
		1015735 RHOG_HUMAN (1-192): 5.1e-79: 235: 70.83		OSB10_HUMAN (3-730): 0: 540: 36.02
+	Hs
		955546 CDC42_HUMAN (1-192): 1.66e-78: 234: 68.75		OSB10_HUMAN (3-730): 0: 540: 36.02
+	Hs
		1015734 RHOG_HUMAN (1-192): 5.1e-79: 235: 70.83		OSB11_HUMAN (7-729): 3.9e-180: 534: 37.08
+	Hs
		988707 RAC1_HUMAN (1-192): 3.43e-86: 253: 92.19		OSBL3_HUMAN (2-735): 1.74e-164: 498: 14.79
+	Hs
		581290 RAC2_HUMAN (1-192): 1.14e-83: 247: 100.00		OSBL3_HUMAN (2-735): 1.74e-164: 498: 14.79
+	Hs
		953673 RAC3_HUMAN (1-191): 4.97e-80: 238: 89.01		OSBL3_HUMAN (2-735): 1.74e-164: 498: 14.79
+	Hs
		1015785 RHOG_HUMAN (1-192): 5.1e-79: 235: 70.83		OSBL3_HUMAN (2-735): 1.74e-164: 498: 14.79
+	Hs
		988680 RAC1_HUMAN (1-192): 3.43e-86: 253: 92.19		OSBL8_HUMAN (156-724): 6.09e-134: 419: 28.43
+	Hs
		581270 RAC2_HUMAN (1-192): 1.14e-83: 247: 100.00		OSBL8_HUMAN (156-724): 6.09e-134: 419: 28.43
+	Hs
		601432 RHOQ_HUMAN (4-190): 1.9e-82: 244: 62.03		OSBL8_HUMAN (156-724): 6.09e-134: 419: 28.43
+	Hs
		953652 RAC3_HUMAN (1-191): 4.97e-80: 238: 89.01		OSBL8_HUMAN (156-724): 6.09e-134: 419: 28.43
+	Hs
		1015750 RHOG_HUMAN (1-192): 5.1e-79: 235: 70.83		OSBL8_HUMAN (156-724): 6.09e-134: 419: 28.43
+	Hs
		955557 CDC42_HUMAN (1-192): 1.66e-78: 234: 68.75		OSBL8_HUMAN (156-724): 6.09e-134: 419: 28.43
+	Sc
		618338 CDC42_YEAST (1-192): 2.32e-77: 231: 67.19		KES1_YEAST (371-716): 3.08e-96: 306: 29.71