HitPredict

Interactor 1: CDK1 (P23572)
Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase)
Gene: CDK1

Interactor 2: CCNE (P54733)
G1/S-specific cyclin-E (DmCycE)
Gene: CycE

Species: Drosophila melanogaster

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.77 1.00 0.881

The method score is based on:

Property Details
Experiments 15575970, 16603075, 17431409, 7809159
Identification Methods two hybrid, two hybrid array, anti bait coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Cyclin_C~Pkinase, Cyclin_N~Pkinase
Common GO terms GO:0000082 - G1/S transition of mitotic cell cycle
GO:0005634 - nucleus
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 297
Dm

1 709
+ Hs
+ Rn
+ Hs
+ Xl
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Xl
+ Mm
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024