Protein: H2L2C8
Alpha-actinin, sarcomeric

Gene: H2L2C8, atn-1
Organism: Caenorhabditis elegans
Interactions: 111
UniProt ID: H2L2C8

Gene Ontology (top 5):
GO:0005509 - calcium ion binding
GO:0005865 - striated muscle thin filament
GO:0005886 - plasma membrane
GO:0030018 - Z disc
GO:0030036 - actin cytoskeleton organization

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

110496

H2L2C8
Alpha-actinin, sarcomeric

2

18

High-throughput

0.754

High

110581

JAC1
Juxtamembrane domain-associated catenin

1

13

High-throughput

0.665

High

107555

G5EFG1
PDZ and LIM domain protein Zasp

3

20

High-throughput

0.639

High

110517

SEM5
Sex muscle abnormal protein 5

3

20

High-throughput

0.639

High

103424

G4S034
Spectrin alpha chain

1

19

Small-scale

0.621

High

110504

PSA6
Proteasome subunit alpha type-6

4

4

High-throughput

0.616

High

110522

LIN36
Protein lin-36

3

15

High-throughput

0.583

High

110528

SUMO
Small ubiquitin-related modifier

3

8

High-throughput

0.583

High

110557

PSB3
Proteasome subunit beta type-3

3

5

High-throughput

0.583

High

110558

Q23482
Uncharacterized protein

3

1

High-throughput

0.583

High

110209

H2L0C1
Fibronectin type-III domain-containing protein

1

11

High-throughput

0.555

High

110505

O17666
Calponin-homology

1

1

High-throughput

0.555

High

105086

G5ECD7
cGMP-dependent protein kinase interacting domain-containing protein

2

19

High-throughput

0.533

High

110509

O61708
Protein lingerer

2

2

High-throughput

0.533

High

110514

PSDE
26S proteasome non-ATPase regulatory subunit 14

2

6

High-throughput

0.533

High

110579

Q9TZA6
BTB domain-containing protein

2

8

High-throughput

0.533

High

110584

PBS5
Proteasome subunit pbs-5

2

2

High-throughput

0.533

High

110530

HMP1
Alpha-catenin-like protein hmp-1

1

12

High-throughput

0.515

High

110538

Q17549
MAGUK p55 subfamily member 5

1

13

High-throughput

0.515

High

106538

G5EE02
TRP homlogous cation channel protein

1

7

High-throughput

0.481

High

110503

O17084
Tandem-repeating region of mucin epiglycanin-like domain-containing protein

1

5

High-throughput

0.481

High

110506

O45313
EF-hand domain-containing protein

1

1

High-throughput

0.481

High

110507

WARTS
Serine/threonine-protein kinase WARTS homolog

1

4

Small-scale

0.481

High

110510

PRY1
Axin-like protein pry-1

1

1

High-throughput

0.481

High

110516

VINC
Vinculin

1

6

Small-scale

0.481

High

110519

PAC1
GTPase-activating protein pac-1

1

4

High-throughput

0.481

High

110527

LIN2
Protein lin-2

1

14

High-throughput

0.481

High

110544

BAR1
Beta-catenin/armadillo-related protein 1

1

8

High-throughput

0.481

High

110550

Q21529
Potassium channel domain-containing protein

1

1

High-throughput

0.481

High

110552

TPM1
Tropomyosin isoforms a/b/d/f

1

3

High-throughput

0.481

High

110562

Q7JNG1
ATP synthase subunit O, mitochondrial

1

3

High-throughput

0.481

High

110588

DTN1
Dystrobrevin-1

1

3

High-throughput

0.481

High

110563

Q86GU1
SHSP domain-containing protein

1

9

Small-scale

0.445

High

59452

A3QM99
Dof-type domain-containing protein

1

1

High-throughput

0.439

High

88177

D3YT29
PDZ domain-containing protein

1

19

High-throughput

0.439

High

92106

E9P8A8
Rab GDP dissociation inhibitor

1

1

High-throughput

0.439

High

103397

CDC26
Anaphase-promoting complex subunit CDC26

1

1

High-throughput

0.439

High

105284

G5ECL3
Pre-RNA processing 21

1

8

High-throughput

0.439

High

105424

G5ECR7
RNA polymerase II transcription factor SIII p18 subunit

1

1

High-throughput

0.439

High

105638

G5ED07
Protein disulfide-isomerase

1

3

High-throughput

0.439

High

107374

G5EF90
DNA-binding protein

1

1

High-throughput

0.439

High

109665

H2KZ17
DiSHevelled related

1

13

High-throughput

0.439

High

110216

H2L0C6
Cep57 centrosome microtubule-binding domain-containing protein

1

1

High-throughput

0.439

High

110497

CSN2
COP9 signalosome complex subunit 2

1

1

High-throughput

0.439

High

110498

O01585
Rho-GAP domain-containing protein

1

3

High-throughput

0.439

High

110499

O01661
Guanylate kinase/L-type calcium channel beta subunit domain-containing protein

1

9

High-throughput

0.439

High

110500

RL7
Large ribosomal subunit protein uL30

1

1

High-throughput

0.439

High

110501

FIGL1
Fidgetin-like protein 1

1

8

High-throughput

0.439

High

110502

O16500
Activated in Blocked Unfolded protein response

1

1

High-throughput

0.439

High

110508

ODBA
2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial

1

4

High-throughput

0.439

High

110511

O62332
Importin N-terminal domain-containing protein

1

1

High-throughput

0.439

High

110512

O76258
Tumor susceptibility gene 101 protein

1

7

High-throughput

0.439

High

110513

O76406
Kinetochore NuLl

1

1

High-throughput

0.439

High

110515

O76642
MATH domain-containing protein

1

1

High-throughput

0.439

High

110518

EIF3D
Eukaryotic translation initiation factor 3 subunit D

1

1

High-throughput

0.439

High

110520

COL90
Putative cuticle collagen 90

1

3

High-throughput

0.439

High

110521

ESS2
Splicing factor ESS-2

1

1

High-throughput

0.439

High

110523

YMX1
Uncharacterized protein K06H7.1

1

1

High-throughput

0.439

High

110524

MPK1
Mitogen-activated protein kinase mpk-1

1

7

High-throughput

0.439

High

110525

RL5
Large ribosomal subunit protein uL18

1

1

High-throughput

0.439

High

110526

GBG
Guanine nucleotide-binding protein subunit gamma

1

1

High-throughput

0.439

High

110529

P90823
7TM GPCR serpentine receptor class x

1

1

High-throughput

0.439

High

110531

EGL26
Egg-laying defective protein 26

1

1

High-throughput

0.439

High

110532

P91175
Pre-mRNA-splicing factor SYF1

1

1

High-throughput

0.439

High

110533

P91457
RanBP2-type domain-containing protein

1

3

High-throughput

0.439

High

110534

P91563
BTB domain-containing protein

1

10

High-throughput

0.439

High

110535

YP69
Uncharacterized protein B0495.9

1

1

High-throughput

0.439

High

110536

NUP35
Nucleoporin NUP35

1

1

High-throughput

0.439

High

110537

PHA4
Defective pharyngeal development protein 4

1

1

High-throughput

0.439

High

110539

Q17746
ZZ-type domain-containing protein

1

2

High-throughput

0.439

High

110540

ELP4
Elongator complex protein 4

1

1

High-throughput

0.439

High

110541

Q18241
Helicase ARIP4

1

5

High-throughput

0.439

High

110542

Q18547
Replication factor C subunit 3

1

1

High-throughput

0.439

High

110543

Q18750
PEHE domain-containing protein

1

1

High-throughput

0.439

High

110545

Q19455
Ovule protein

1

1

High-throughput

0.439

High

110546

Q19465
Neuropeptide-Like Protein

1

1

High-throughput

0.439

High

110547

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

1

2

High-throughput

0.439

High

110548

Q20770
DUF19 domain-containing protein

1

1

High-throughput

0.439

High

110549

Q21015
EGF-like domain-containing protein

1

1

High-throughput

0.439

High

110551

Q22559
PDZ domain-containing protein

1

1

High-throughput

0.439

High

110553

Q22966
C-type lectin domain-containing protein

1

11

High-throughput

0.439

High

110554

UNC51
Serine/threonine-protein kinase unc-51

1

5

High-throughput

0.439

High

110555

TTC8
Tetratricopeptide repeat protein 8

1

5

High-throughput

0.439

High

110556

UNC83
Nuclear migration protein unc-83

1

1

Small-scale

0.439

High

110559

Q23546
non-specific serine/threonine protein kinase

1

2

High-throughput

0.439

High

110560

VATF
Probable V-type proton ATPase subunit F

1

1

High-throughput

0.439

High

110561

Q6AW08
Conserved oligomeric Golgi complex subunit 3

1

1

High-throughput

0.439

High

110564

Q8MXR2
RRM domain-containing protein

1

8

High-throughput

0.439

High

110565

RGS7
Regulator of G-protein signaling rgs-7

1

8

High-throughput

0.439

High

110566

MBK1
Dual specificity tyrosine-phosphorylation-regulated kinase mbk-1

1

9

High-throughput

0.439

High

110567

Q93696
Glutathione transferase

1

1

High-throughput

0.439

High

110568

Q94241
Vesicle-trafficking protein SEC22b

1

3

High-throughput

0.439

High

110569

UBC9
SUMO-conjugating enzyme UBC9

1

2

High-throughput

0.439

High

110570

PAT12
Protein pat-12

1

4

High-throughput

0.439

High

110571

DCLK
Serine/threonine-protein kinase zyg-8

1

18

High-throughput

0.439

High

110572

GPR1
G-protein regulator 1

1

1

High-throughput

0.439

High

110573

Q95Y13
Nucleoporin Nup133/Nup155-like N-terminal domain-containing protein

1

1

High-throughput

0.439

High

110574

Q9GYG1
C2H2-type domain-containing protein

1

1

High-throughput

0.439

High

110575

Q9GYR3
Neuropeptide-Like Protein

1

1

High-throughput

0.439

High

110576

Q9N3F4
RNA helicase

1

2

High-throughput

0.439

High

110577

Q9N499
CC domain-containing protein

1

1

High-throughput

0.439

High

110578

Q9N580
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

1

1

High-throughput

0.439

High

110580

Q9U304
RRM domain-containing protein

1

6

High-throughput

0.439

High

110582

Q9U3B9
Nucleoporin Nup54 alpha-helical domain-containing protein

1

5

High-throughput

0.439

High

110583

MBK2
Dual specificity tyrosine-phosphorylation-regulated kinase mbk-2

1

9

High-throughput

0.439

High

110585

Q9XVF6
CAlcium channel Localization Factor

1

1

High-throughput

0.439

High

110586

Q9XVW8
ZM domain-containing protein

1

1

High-throughput

0.439

High

110587

Q9XWK3
Nucleoporin p58/p45

1

4

High-throughput

0.439

High

70248

TBPL1
TATA box-binding protein-like 1

1

0

High-throughput

0.251

Low

110236

H2L0E0
SET domain-containing protein

1

0

High-throughput

0.251

Low


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Last updated: 15 Jul 2024