HitPredict

Interactor 1: IF4B (P23588)
Eukaryotic translation initiation factor 4B (eIF-4B)
Gene: EIF4B

Interactor 2: G3BP2 (Q9UN86)
Ras GTPase-activating protein-binding protein 2 (G3BP-2) (GAP SH3 domain-binding protein 2)
Gene: G3BP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 611 Hs			1 482
+	Hs
		618614 IF4B_HUMAN (1-611): 6.54e-98: 313: 100.00		G3BP1_HUMAN (1-460): 6.81e-83: 265: 56.81
+	Hs
		516742 PABP1_HUMAN (49-537): 3.4e-25: 112: 10.22		G3BP2_HUMAN (1-482): 5.94e-108: 330: 100.00
+	Hs
		1031497 PABP4_HUMAN (49-389): 1.92e-21: 100: 9.72		G3BP2_HUMAN (1-482): 5.94e-108: 330: 100.00
+	Hs
		1030251 IF4H_HUMAN (83-245): 1.61e-38: 144: 33.13		G3BP1_HUMAN (1-460): 6.81e-83: 265: 56.81
+	Hs
		1030411 MSI2H_HUMAN (82-179): 1.19e-27: 115: 18.37		G3BP1_HUMAN (1-460): 6.81e-83: 265: 56.81
+	Hs
		516494 PABP1_HUMAN (49-537): 3.4e-25: 112: 10.22		G3BP1_HUMAN (1-460): 6.81e-83: 265: 56.81
+	Zm
		22429 A0A1D6I0G1_MAIZE (10-400): 5.79e-40: 157: 12.90		A0A1D6Q2L8_MAIZE (6-475): 6.16e-65: 218: 23.80
+	Hs
		1030211 PABP4_HUMAN (49-389): 1.92e-21: 100: 9.72		G3BP1_HUMAN (1-460): 6.81e-83: 265: 56.81
+	Hs
		1030413 DAZP1_HUMAN (97-186): 2.18e-21: 98.8: 17.78		G3BP1_HUMAN (1-460): 6.81e-83: 265: 56.81
+	Sc
		376881 PABP_YEAST (7-185): 1.17e-23: 107: 16.58		BRE5_YEAST (9-419): 2.98e-56: 197: 15.59
+	Sc
		648407 NSR1_YEAST (84-187): 1.96e-10: 65.3: 20.00		BRE5_YEAST (9-419): 2.98e-56: 197: 15.59
+	Hs
		516621 PABP1_HUMAN (49-537): 3.4e-25: 112: 10.22		CELF1_HUMAN (323-419): 4.95e-15: 79.2: 18.63
+	Hs
		201689 MSI1H_HUMAN (88-180): 1.42e-23: 104: 22.58		CELF5_HUMAN (293-418): 4.09e-17: 85.7: 17.83
+	Hs
		201697 MSI1H_HUMAN (88-180): 1.42e-23: 104: 22.58		CELF1_HUMAN (323-419): 4.95e-15: 79.2: 18.63
+	Hs
		1031413 PABP4_HUMAN (49-389): 1.92e-21: 100: 9.72		CELF1_HUMAN (323-419): 4.95e-15: 79.2: 18.63
+	Hs
		1272074 DAZP1_HUMAN (97-186): 2.18e-21: 98.8: 17.78		CELF1_HUMAN (323-419): 4.95e-15: 79.2: 18.63