Protein: MYL9
Myosin regulatory light polypeptide 9 (20 kDa myosin light chain) (LC20) (MLC-2C) (Myosin RLC) (Myosin regulatory light chain 2, smooth muscle isoform) (Myosin regulatory light chain 9) (Myosin regulatory light chain MRLC1)

Gene: MYL9
Organism: Homo sapiens
Interactions: 65
UniProt ID: P24844

Gene Ontology (top 5):
GO:0001725 - stress fiber
GO:0005200 - structural constituent of cytoskeleton
GO:0005509 - calcium ion binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

666740

MYH9
Myosin-9

4

19

High-throughput

0.898

High

666757

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

2

11

Small-scale

0.789

High

666741

MYH10
Myosin-10

2

20

High-throughput

0.789

High

169059

ML12B
Myosin regulatory light chain 12B

2

13

High-throughput

0.737

High

666764

THIOM
Thioredoxin, mitochondrial

2

4

High-throughput

0.700

High

618646

ML12A
Myosin regulatory light chain 12A

1

16

High-throughput

0.691

High

666780

AKT3
RAC-gamma serine/threonine-protein kinase

1

3

High-throughput

0.691

High

666750

AAPK1
5'-AMP-activated protein kinase catalytic subunit alpha-1

1

11

Small-scale

0.666

High

563219

CFTR
Cystic fibrosis transmembrane conductance regulator

3

3

High-throughput

0.650

High

156970

CTRO
Citron Rho-interacting kinase

1

18

High-throughput

0.618

High

666745

PLK1
Serine/threonine-protein kinase PLK1

1

17

High-throughput

0.618

High

666751

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

11

High-throughput

0.618

High

666754

MYLK
Myosin light chain kinase, smooth muscle

1

18

High-throughput

0.618

High

666760

CC141
Coiled-coil domain-containing protein 141

1

20

Small-scale

0.618

High

666763

AURKB
Aurora kinase B

1

8

High-throughput

0.618

High

666765

SIK2
Serine/threonine-protein kinase SIK2

1

9

Small-scale

0.618

High

666779

PRP19
Pre-mRNA-processing factor 19

1

2

Small-scale

0.578

High

415353

HSPB1
Heat shock protein beta-1

1

6

High-throughput

0.541

High

573923

MYL6B
Myosin light chain 6B

1

20

High-throughput

0.536

High

666743

CAPZB
F-actin-capping protein subunit beta

1

3

High-throughput

0.536

High

666746

MYL6
Myosin light polypeptide 6

1

20

High-throughput

0.536

High

666772

NOD2
Nucleotide-binding oligomerization domain-containing protein 2

1

2

High-throughput

0.536

High

666766

FOXP1
Forkhead box protein P1

1

4

High-throughput

0.489

High

666778

FOXD3
Forkhead box protein D3

1

2

High-throughput

0.489

High

186701

P73
Tumor protein p73

1

5

High-throughput

0.479

High

222729

PRC1
Protein regulator of cytokinesis 1

1

7

High-throughput

0.479

High

323178

TRI37
E3 ubiquitin-protein ligase TRIM37

1

6

High-throughput

0.479

High

324543

HEXI1
Protein HEXIM1

1

2

High-throughput

0.479

High

330668

KI20A
Kinesin-like protein KIF20A

1

12

High-throughput

0.479

High

413212

P53
Cellular tumor antigen p53

1

5

High-throughput

0.479

High

464816

SP1
Transcription factor Sp1

1

4

Small-scale

0.479

High

629568

BTF3
Transcription factor BTF3

1

4

High-throughput

0.479

High

651155

CBL
E3 ubiquitin-protein ligase CBL

1

6

High-throughput

0.479

High

666742

YAP1
Transcriptional coactivator YAP1

1

2

High-throughput

0.479

High

666744

MCM2
DNA replication licensing factor MCM2

1

2

High-throughput

0.479

High

666748

KIF23
Kinesin-like protein KIF23

1

9

High-throughput

0.479

High

666749

TFCP2
Alpha-globin transcription factor CP2

1

1

High-throughput

0.479

High

666752

TNIP1
TNFAIP3-interacting protein 1

1

20

High-throughput

0.479

High

666753

KIF14
Kinesin-like protein KIF14

1

6

High-throughput

0.479

High

666756

LARP7
La-related protein 7

1

3

High-throughput

0.479

High

666759

FGD5
FYVE, RhoGEF and PH domain-containing protein 5

1

6

High-throughput

0.479

High

666761

FBX25
F-box only protein 25

1

2

High-throughput

0.479

High

666762

OPTN
Optineurin

1

20

High-throughput

0.479

High

666767

P63
Tumor protein 63

1

5

High-throughput

0.479

High

666769

CHM4B
Charged multivesicular body protein 4b

1

3

High-throughput

0.479

High

666770

PKHA4
Pleckstrin homology domain-containing family A member 4

1

14

High-throughput

0.479

High

666771

ECT2
Protein ECT2

1

7

High-throughput

0.479

High

666773

ANLN
Anillin

1

4

High-throughput

0.479

High

666776

HDAC6
Protein deacetylase HDAC6

1

3

High-throughput

0.479

High

666777

TES
Testin

1

7

High-throughput

0.479

High

666738

CCND2
G1/S-specific cyclin-D2

1

0

Small-scale

0.458

High

666737

S10A4
Protein S100-A4

1

2

High-throughput

0.445

High

666739

BMI1
Polycomb complex protein BMI-1

1

4

High-throughput

0.445

High

666747

OCRL
Inositol polyphosphate 5-phosphatase OCRL

1

2

High-throughput

0.445

High

666774

DISC1
Disrupted in schizophrenia 1 protein

1

1

Small-scale

0.445

High

178184

NPC1
NPC intracellular cholesterol transporter 1

1

1

High-throughput

0.437

High

371190

MYC
Myc proto-oncogene protein

1

4

High-throughput

0.437

High

666755

MICB
MHC class I polypeptide-related sequence B

1

3

High-throughput

0.437

High

666758

TET2
Methylcytosine dioxygenase TET2

1

1

Small-scale

0.437

High

104388

F5H7Q8
MHC class I polypeptide-related sequence B

1

3

High-throughput

0.407

High

666781

ITM2B
Integral membrane protein 2B

1

4

High-throughput

0.407

High

65871

MSGN1
Mesogenin-1

2

0

High-throughput

0.316

High

666768

TCAL2
Transcription elongation factor A protein-like 2

1

0

High-throughput

0.279

Low

666775

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

0

High-throughput

0.249

Low

666782

TRRAP
Transformation/transcription domain-associated protein

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025