HitPredict

Interactor 1: VCAM1 (P19320)
Vascular cell adhesion protein 1 (V-CAM 1) (VCAM-1) (INCAM-100) (CD antigen CD106) [Cleaved into: Soluble Vascular Cell Adhesion Molecule-1]
Gene: VCAM1

Interactor 2: TADBP (Q13148)
TAR DNA-binding protein 43 (TDP-43)
Gene: TARDBP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.50	0.521

Property	Details
Experiments	19738201, 22623428
Identification Methods	affinity chromatography technology, cross-linking study
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 739 Hs			1 414
+	Hs
		172014 VCAM1_HUMAN (1-739): 2.08e-154: 468: 100.00		HNRDL_HUMAN (62-376): 5.65e-71: 231: 23.60
+	Hs
		619626 VCAM1_HUMAN (1-739): 2.08e-154: 468: 100.00		ROA3_HUMAN (98-269): 2.35e-69: 225: 28.57
+	Hs
		619778 VCAM1_HUMAN (1-739): 2.08e-154: 468: 100.00		PABP4_HUMAN (98-275): 1.57e-37: 146: 18.92
+	Hs
		619538 VCAM1_HUMAN (1-739): 2.08e-154: 468: 100.00		TIA1_HUMAN (99-414): 3.86e-38: 143: 13.57
+	Hs
		619787 VCAM1_HUMAN (1-739): 2.08e-154: 468: 100.00		HNRPD_HUMAN (81-238): 5.61e-21: 95.1: 35.93
+	Hs
		619889 VCAM1_HUMAN (1-739): 2.08e-154: 468: 100.00		MSI2H_HUMAN (41-207): 4.63e-20: 92.2: 23.81
+	Hs
		550113 VCAM1_HUMAN (1-739): 2.08e-154: 468: 100.00		PABP1_HUMAN (181-270): 2.86e-10: 64: 20.62
+	Hs
		1096129 TITIN_HUMAN (11-129): 1.35e-09: 64.2: 11.72		TADBP_HUMAN (1-414): 1.68e-85: 268: 100.00
+	Hs
		172156 TITIN_HUMAN (11-129): 1.35e-09: 64.2: 11.72		HNRDL_HUMAN (62-376): 5.65e-71: 231: 23.60
+	Hs
		629544 CD22_HUMAN (10-451): 2.48e-36: 149: 17.00		TIA1_HUMAN (99-414): 3.86e-38: 143: 13.57
+	Hs
		1102036 TITIN_HUMAN (11-129): 1.35e-09: 64.2: 11.72		PABP4_HUMAN (98-275): 1.57e-37: 146: 18.92
+	Hs
		550381 TITIN_HUMAN (11-129): 1.35e-09: 64.2: 11.72		PABP1_HUMAN (181-270): 2.86e-10: 64: 20.62