HitPredict

Interactor 1: PHOP (P23836)
Transcriptional regulatory protein PhoP
Gene: PHOP

Interactor 2: PHOP (P23836)
Transcriptional regulatory protein PhoP
Gene: PHOP

Species: Escherichia coli K-12

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.74 1.00 0.864

The method score is based on:

Property Details
Experiments 24561554, 17545283, 18631241
Identification Methods two hybrid, molecular sieving, x-ray crystallography, fluorescent resonance energy transfer, two hybrid array
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Response_reg~Response_reg, Response_reg~Trans_reg_C, Trans_reg_C~Trans_reg_C
Common GO terms GO:0000156 - phosphorelay response regulator activity
GO:0000976 - transcription cis-regulatory region binding
GO:0001216 - DNA-binding transcription activator activity
GO:0005829 - cytosol
GO:0006355 - regulation of DNA-templated transcription
and 2 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 223
Ec

1 223
+ Ec
+ Ec
+ Ss
+ Ec
+ Mx
+ Ec
+ Mx
+ Ec
+ Ec
+ Ec
+ Ec
+ Ec
+ Mx
+ Mx
+ Ec
+ Mx
+ Mx

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Last updated: 15 Jul 2024