Protein: ARRD1
Arrestin domain-containing protein 1 (Alpha-arrestin 1)

Gene: ARRD1, ARRDC1
Organism: Homo sapiens
Interactions: 66
UniProt ID: Q8N5I2

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0006858 - extracellular transport
GO:0015031 - protein transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

132163

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

11

20

Small-scale

0.757

High

458445

ADRB2
Beta-2 adrenergic receptor

2

10

Small-scale

0.757

High

1327833

ITCH
E3 ubiquitin-protein ligase Itchy homolog

8

20

Small-scale

0.751

High

1327840

WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1

7

20

Small-scale

0.748

High

861682

NEDD4
E3 ubiquitin-protein ligase NEDD4

6

20

Small-scale

0.733

High

1327835

NED4L
E3 ubiquitin-protein ligase NEDD4-like

5

20

High-throughput

0.716

High

1327848

HECW2
E3 ubiquitin-protein ligase HECW2

5

20

High-throughput

0.716

High

862296

YAP1
Transcriptional coactivator YAP1

5

20

Small-scale

0.712

High

1327836

TS101
Tumor susceptibility gene 101 protein

4

4

Small-scale

0.706

High

1130011

KCTD2
BTB/POZ domain-containing protein KCTD2

4

5

High-throughput

0.691

High

1311631

KIBRA
Protein KIBRA

4

20

High-throughput

0.691

High

1327825

KCD17
BTB/POZ domain-containing protein KCTD17

4

4

High-throughput

0.691

High

1327839

OSBL6
Oxysterol-binding protein-related protein 6

4

1

High-throughput

0.691

High

1327841

OSBL3
Oxysterol-binding protein-related protein 3

4

1

High-throughput

0.691

High

1327849

ZMYM2
Zinc finger MYM-type protein 2

6

2

High-throughput

0.668

High

1327853

EPN1
Epsin-1

3

5

High-throughput

0.667

High

1199003

KLH12
Kelch-like protein 12

3

3

High-throughput

0.665

High

1327846

KCTD5
BTB/POZ domain-containing protein KCTD5

3

5

High-throughput

0.650

High

1136916

ABRX2
BRISC complex subunit Abraxas 2

3

0

High-throughput

0.638

High

1327831

GLMN
Glomulin

3

0

High-throughput

0.638

High

1327837

CND3
Condensin complex subunit 3

3

0

High-throughput

0.634

High

1327845

CUED1
CUE domain-containing protein 1

4

1

High-throughput

0.630

High

882530

ARRB1
Beta-arrestin-1

1

15

Small-scale

0.618

High

1315809

AN13A
Ankyrin repeat domain-containing protein 13A

2

4

High-throughput

0.611

High

1208369

WIPI3
WD repeat domain phosphoinositide-interacting protein 3

3

8

High-throughput

0.609

High

1327834

TOPK
Lymphokine-activated killer T-cell-originated protein kinase

3

1

High-throughput

0.609

High

1327847

RCOR3
REST corepressor 3

3

3

High-throughput

0.609

High

1327851

RCOR1
REST corepressor 1

3

3

High-throughput

0.609

High

329467

EPN2
Epsin-2

2

5

High-throughput

0.606

High

943793

UBS3A
Ubiquitin-associated and SH3 domain-containing protein A

2

1

High-throughput

0.606

High

1327850

VPS28
Vacuolar protein sorting-associated protein 28 homolog

2

0

High-throughput

0.585

High

1325107

MTURN
Maturin

2

0

High-throughput

0.580

High

246758

KDM1A
Lysine-specific histone demethylase 1A

2

4

High-throughput

0.558

High

920480

DAPK1
Death-associated protein kinase 1

1

3

High-throughput

0.536

High

183278

LAMA5
Laminin subunit alpha-5

1

5

High-throughput

0.536

High

318360

MYO1D
Unconventional myosin-Id

1

16

High-throughput

0.536

High

414205

P53
Cellular tumor antigen p53

1

3

High-throughput

0.536

High

535869

LAMC1
Laminin subunit gamma-1

1

5

High-throughput

0.536

High

572694

NID1
Nidogen-1

1

3

High-throughput

0.536

High

667368

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

6

High-throughput

0.536

High

862677

UTRN
Utrophin

1

11

High-throughput

0.536

High

937415

LAMB2
Laminin subunit beta-2

1

5

High-throughput

0.536

High

1310756

CUL9
Cullin-9

1

8

High-throughput

0.536

High

1325653

FGRL1
Fibroblast growth factor receptor-like 1

1

4

High-throughput

0.536

High

1327838

GTR11
Solute carrier family 2, facilitated glucose transporter member 11

1

7

High-throughput

0.536

High

1327842

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

20

High-throughput

0.536

High

1327852

MYO5A
Unconventional myosin-Va

1

7

High-throughput

0.536

High

1327827

PDC6I
Programmed cell death 6-interacting protein

1

7

Small-scale

0.527

High

164390

NRP1
Neuropilin-1

1

0

High-throughput

0.513

High

713172

NOS1
Nitric oxide synthase 1

1

0

High-throughput

0.513

High

422585

A4
Amyloid-beta precursor protein

1

4

High-throughput

0.501

High

673779

LAMA1
Laminin subunit alpha-1

1

5

High-throughput

0.489

High

829460

ECHA
Trifunctional enzyme subunit alpha, mitochondrial

1

2

High-throughput

0.489

High

907498

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

5

High-throughput

0.489

High

173069

XPO1
Exportin-1

1

9

High-throughput

0.479

High

860559

RS5
Small ribosomal subunit protein uS7

1

0

High-throughput

0.458

High

909346

UB2E1
Ubiquitin-conjugating enzyme E2 E1

1

7

High-throughput

0.457

High

1327830

NELL1
Protein kinase C-binding protein NELL1

1

2

High-throughput

0.445

High

1327829

ESR2
Estrogen receptor beta

1

3

High-throughput

0.437

High

1327844

TBC23
TBC1 domain family member 23

1

0

High-throughput

0.426

High

1327832

UB2E3
Ubiquitin-conjugating enzyme E2 E3

1

7

High-throughput

0.417

High

1327826

VP37A
Vacuolar protein sorting-associated protein 37A

3

0

High-throughput

0.347

High

1231731

NXN
Nucleoredoxin

2

0

High-throughput

0.318

High

935918

ECHB
Trifunctional enzyme subunit beta, mitochondrial

1

0

High-throughput

0.279

Low

1327828

F168A
Protein FAM168A

1

0

High-throughput

0.279

Low

1327843

RT30
Large ribosomal subunit protein mL65

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025