HitPredict

Interactor 1: PRTN3 (P24158)
Myeloblastin (EC 3.4.21.76) (AGP7) (C-ANCA antigen) (Leukocyte proteinase 3) (PR-3) (PR3) (Neutrophil proteinase 4) (NP-4) (P29) (Wegener autoantigen)
Gene: PRTN3

Interactor 2: XIAP (P98170)
E3 ubiquitin-protein ligase XIAP (EC 2.3.2.27) (Baculoviral IAP repeat-containing protein 4) (IAP-like protein) (ILP) (hILP) (Inhibitor of apoptosis protein 3) (IAP-3) (hIAP-3) (hIAP3) (RING-type E3 ubiquitin transferase XIAP) (X-linked inhibitor of apoptosis protein) (X-linked IAP)
Gene: XIAP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 256 Hs			1 497
+	Hs
		621780 PRTN3_HUMAN (1-256): 5.43e-109: 316: 100.00		BIRC2_HUMAN (3-497): 9.73e-82: 267: 23.31
+	Hs
		621823 PRTN3_HUMAN (1-256): 5.43e-109: 316: 100.00		BIRC6_HUMAN (258-442): 3.1e-26: 115: 18.78
+	Hs
		884424 TMPS3_HUMAN (1-249): 1.95e-95: 288: 27.99		CGRF1_HUMAN (317-491): 2.2e-23: 102: 14.29
+	Hs
		178010 TMPS2_HUMAN (1-248): 2.73e-89: 274: 27.14		BIRC6_HUMAN (258-442): 3.1e-26: 115: 18.78
+	Hs
		1305534 TMPS4_HUMAN (5-246): 3.48e-92: 280: 26.54		CGRF1_HUMAN (317-491): 2.2e-23: 102: 14.29
+	Hs
		177980 TMPS2_HUMAN (1-248): 2.73e-89: 274: 27.14		CGRF1_HUMAN (317-491): 2.2e-23: 102: 14.29
+	Hs
		1206070 TMPS4_HUMAN (5-246): 3.48e-92: 280: 26.54		MIB1_HUMAN (311-492): 5.04e-16: 83.1: 13.68
+	Hs
		1271931 KLK6_HUMAN (9-250): 1.54e-91: 271: 30.16		RNF34_HUMAN (440-497): 1.43e-18: 89.2: 37.93
+	Hs
		439082 ELNE_HUMAN (1-256): 8.71e-90: 268: 53.13		MIB2_HUMAN (437-496): 2e-10: 65.3: 35.00