HitPredict

Interactor 1: GRIA2 (P19491)
Glutamate receptor 2 (GluR-2) (AMPA-selective glutamate receptor 2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2)
Gene: GRIA2

Interactor 2: CCG5 (Q8VHW8)
Voltage-dependent calcium channel gamma-5 subunit (Neuronal voltage-gated calcium channel gamma-5 subunit) (Transmembrane AMPAR regulatory protein gamma-5) (TARP gamma-5)
Gene: Cacng5

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	37653241
Identification Methods	x-ray crystallography
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0014069 - postsynaptic density GO:0032281 - AMPA glutamate receptor complex GO:0045211 - postsynaptic membrane GO:0098839 - postsynaptic density membrane GO:0098978 - glutamatergic synapse
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 883 Rn			1 275
+	Hs
		838519 GRIA2_HUMAN (1-883): 0: 918: 99.55		CCG2_HUMAN (1-218): 1.03e-70: 222: 29.15
+	Mm
		312690 GRIA2_MOUSE (1-883): 0: 917: 99.89		CCG2_MOUSE (1-218): 1.37e-70: 221: 29.15
+	Rn
		623687 GRIA2_RAT (1-883): 0: 917: 100.00		CCG2_RAT (1-218): 1.37e-70: 221: 29.15
+	Rn
		623692 GRIA2_RAT (1-883): 0: 917: 100.00		Q99PR9_RAT (1-218): 1.37e-70: 221: 29.15
+	Rn
		623689 GRIA2_RAT (1-883): 0: 917: 100.00		CCG8_RAT (4-207): 3.94e-66: 213: 29.86
+	Mm
		663159 GRIA2_MOUSE (1-883): 0: 917: 99.89		CCG8_MOUSE (4-207): 6.03e-66: 213: 29.86
+	Mm
		663191 GRIA2_MOUSE (1-883): 0: 917: 99.89		CCG3_MOUSE (1-218): 3.12e-67: 213: 30.36
+	Hs
		838476 GRIA1_HUMAN (4-868): 0: 859: 70.09		CCG2_HUMAN (1-218): 1.03e-70: 222: 29.15
+	Rn
		623664 GRIA1_RAT (4-868): 0: 855: 69.75		CCG2_RAT (1-218): 1.37e-70: 221: 29.15
+	Hs
		838462 GRIA1_HUMAN (4-868): 0: 859: 70.09		CCG8_HUMAN (4-207): 1e-66: 215: 30.18
+	Mm
		312689 GRIA1_MOUSE (4-868): 0: 851: 68.82		CCG2_MOUSE (1-218): 1.37e-70: 221: 29.15
+	Rn
		623666 GRIA1_RAT (4-868): 0: 855: 69.75		CCG8_RAT (4-207): 3.94e-66: 213: 29.86
+	Mm
		663051 GRIA1_MOUSE (4-868): 0: 851: 68.82		CCG3_MOUSE (1-218): 3.12e-67: 213: 30.36
+	Hs
		870114 GRIA4_HUMAN (1-848): 0: 839: 73.19		CCG2_HUMAN (1-218): 1.03e-70: 222: 29.15
+	Ce
		111974 GLR1_CAEEL (3-845): 0: 604: 35.67		G5EDT2_CAEEL (1-211): 4.02e-53: 178: 20.61