HitPredict

Interactor 1: GRIA2 (P23819)
Glutamate receptor 2 (GluR-2) (AMPA-selective glutamate receptor 2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2)
Gene: GRIA2

Interactor 2: CCG3 (Q9JJV5)
Voltage-dependent calcium channel gamma-3 subunit (Neuronal voltage-gated calcium channel gamma-3 subunit) (Transmembrane AMPAR regulatory protein gamma-3) (TARP gamma-3)
Gene: Cacng3

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36417873
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Lig_chan~PMP22_Claudin, Lig_chan-Glu_bd~PMP22_Claudin
Common GO terms	GO:0030425 - dendrite GO:0032281 - AMPA glutamate receptor complex GO:0036477 - somatodendritic compartment GO:0098685 - Schaffer collateral - CA1 synapse GO:0098839 - postsynaptic density membrane and 1 others more... GO:0098978 - glutamatergic synapse
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 883 Mm			1 315
+	Hs
		838519 GRIA2_HUMAN (1-883): 0: 911: 99.66		CCG2_HUMAN (1-315): 3.22e-120: 350: 70.90
+	Mm
		312690 GRIA2_MOUSE (1-883): 0: 909: 100.00		CCG2_MOUSE (1-315): 2.51e-119: 347: 70.59
+	Rn
		623687 GRIA2_RAT (1-883): 0: 908: 99.89		CCG2_RAT (1-315): 2.51e-119: 347: 70.59
+	Rn
		623692 GRIA2_RAT (1-883): 0: 908: 99.89		Q99PR9_RAT (1-315): 5.95e-119: 346: 70.59
+	Mm
		663051 GRIA1_MOUSE (4-862): 0: 842: 69.05		CCG3_MOUSE (1-315): 7.07e-133: 381: 100.00
+	Hs
		838476 GRIA1_HUMAN (4-862): 0: 850: 70.32		CCG2_HUMAN (1-315): 3.22e-120: 350: 70.90
+	Rn
		623664 GRIA1_RAT (4-862): 0: 846: 69.98		CCG2_RAT (1-315): 2.51e-119: 347: 70.59
+	Rn
		623689 GRIA2_RAT (1-883): 0: 908: 99.89		CCG8_RAT (4-315): 1.41e-93: 285: 44.72
+	Mm
		663159 GRIA2_MOUSE (1-883): 0: 909: 100.00		CCG8_MOUSE (4-315): 2.61e-92: 282: 44.25
+	Mm
		312689 GRIA1_MOUSE (4-862): 0: 842: 69.05		CCG2_MOUSE (1-315): 2.51e-119: 347: 70.59
+	Hs
		870114 GRIA4_HUMAN (1-860): 0: 835: 72.29		CCG2_HUMAN (1-315): 3.22e-120: 350: 70.90
+	Rn
		623690 GRIA2_RAT (1-883): 0: 908: 99.89		CCG5_RAT (1-242): 1.61e-73: 229: 28.13
+	Rn
		623666 GRIA1_RAT (4-862): 0: 846: 69.98		CCG8_RAT (4-315): 1.41e-93: 285: 44.72
+	Hs
		838462 GRIA1_HUMAN (4-862): 0: 850: 70.32		CCG8_HUMAN (4-315): 2.41e-88: 272: 43.07
+	Ce
		111974 GLR1_CAEEL (3-864): 0: 597: 35.33		G5EDT2_CAEEL (1-243): 1.4e-62: 204: 19.12