Interactor 1: CCNE1 (P24864)
G1/S-specific cyclin-E1
Gene: CCNE1

Interactor 2: FBXW7 (Q969H0)
F-box/WD repeat-containing protein 7 (Archipelago homolog) (hAgo) (F-box and WD-40 domain-containing protein 7) (F-box protein FBX30) (SEL-10) (hCdc4)
Gene: FBXW7

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 0.60 0.768

The method score is based on:

Property Details
Experiments 14739463, 35089787, 36278408, 15364936, 11565034, 21070969, 19956254, 28209614, 28850619, 14536078, 31152129, 31868589, 32051583, 33288957, 17646408, 34741373, 37028429, 17434132, 16818231, 15980150 and 6 others

more...

Identification Methods unspecified method, pull down, enzymatic study, affinity chromatography technology, x-ray crystallography, coimmunoprecipitation, experimental interaction detection
Interaction Type direct interaction, physical association, association, ubiquitination reaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0032880 - regulation of protein localization
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 410
Hs

1 707
+ Hs
+ Dm
+ Hs
+ Sp
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024