HitPredict

Interactor 1: CDK2 (P24941)
Cyclin-dependent kinase 2 (EC 2.7.11.22) (Cell division protein kinase 2) (p33 protein kinase)
Gene: CDK2

Interactor 2: CUL1 (Q13616)
Cullin-1 (CUL-1)
Gene: CUL1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.84	0.60	0.714

Property	Details
Experiments	21145461, 26186194, 28514442, 9636170, 9736735
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000082 - G1/S transition of mitotic cell cycle GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 298 Hs			1 776
+	Hs
		960092 CDK3_HUMAN (1-294): 1.8e-154: 435: 76.87		CUL1_HUMAN (1-776): 0: 911: 100.00
+	Hs
		414908 CDK1_HUMAN (1-289): 7.44e-144: 408: 66.90		CUL1_HUMAN (1-776): 0: 911: 100.00
+	Hs
		625417 CDK2_HUMAN (1-298): 8.79e-167: 466: 100.00		CUL4B_HUMAN (7-776): 0: 773: 29.90
+	Hs
		414909 CDK1_HUMAN (1-289): 7.44e-144: 408: 66.90		CUL3_HUMAN (9-776): 0: 748: 30.47
+	Hs
		960361 CDK16_HUMAN (1-286): 4.1e-107: 322: 55.40		CUL3_HUMAN (9-776): 0: 748: 30.47