HitPredict

Interactor 1: PAR1 (P25116)
Proteinase-activated receptor 1 (PAR-1) (Coagulation factor II receptor) (Thrombin receptor)
Gene: F2R

Interactor 2: GNA13 (Q14344)
Guanine nucleotide-binding protein subunit alpha-13 (G alpha-13) (G-protein subunit alpha-13)
Gene: GNA13

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 1.00 0.776

The method score is based on:

Property Details
Experiments 23773523, 8290554
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains 7tm_1~G-alpha
Common GO terms GO:0005886 - plasma membrane
GO:0007204 - positive regulation of cytosolic calcium ion concentration
GO:0030168 - platelet activation
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 425
Hs

1 377
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024