Interactor 1: CCND1 (P25322)
G1/S-specific cyclin-D1
Gene: CCND1

Interactor 2: CDN1A (P39689)
Cyclin-dependent kinase inhibitor 1 (CDK-interacting protein 1) (Melanoma differentiation-associated protein) (p21)
Gene: Cdkn1a

Species: Mus musculus

Source: dip

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.79 1.00 0.892

The method score is based on:

Property Details
Experiments 17081987, 12588994, 18729080, 10348346
Identification Methods affinity chromatography technology, biochemical, coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains CDI~Cyclin_N
Common GO terms GO:0000307 - cyclin-dependent protein kinase holoenzyme complex
GO:0001934 - positive regulation of protein phosphorylation
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
and 6 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 295
Mm

1 159
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+ Xl
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+ Hs
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+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024