HitPredict

Interactor 1: POTEF (A5A3E0)
POTE ankyrin domain family member F (ANKRD26-like family C member 1B) (Chimeric POTE-actin protein)
Gene: POTEF

Interactor 2: SCIN (Q9Y6U3)
Scinderin (Adseverin)
Gene: SCIN

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Actin~Gelsolin
Common GO terms	GO:0005737 - cytoplasm GO:0005938 - cell cortex GO:0015629 - actin cytoskeleton GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1075 Hs			1 715
+	Hs
		507007 POTEI_HUMAN (1-1075): 0: 1113: 96.74		SCIN_HUMAN (1-715): 0: 1071: 100.00
+	Hs
		62885 POTEF_HUMAN (1-1075): 0: 1116: 100.00		GELS_HUMAN (2-715): 0: 1033: 59.86
+	Hs
		442210 POTEI_HUMAN (1-1075): 0: 1113: 96.74		GELS_HUMAN (2-715): 0: 1033: 59.86
+	Hs
		953222 ACTB_HUMAN (701-1075): 0: 584: 91.47		SCIN_HUMAN (1-715): 0: 1071: 100.00
+	Hs
		993410 ACTG_HUMAN (701-1075): 0: 584: 90.93		SCIN_HUMAN (1-715): 0: 1071: 100.00
+	Hs
		977870 ACTA_HUMAN (701-1075): 0: 579: 86.40		SCIN_HUMAN (1-715): 0: 1071: 100.00
+	Hs
		995924 ACTC_HUMAN (701-1075): 0: 579: 86.67		SCIN_HUMAN (1-715): 0: 1071: 100.00
+	Hs
		442280 ACTB_HUMAN (701-1075): 0: 584: 91.47		GELS_HUMAN (2-715): 0: 1033: 59.86
+	Hs
		442290 ACTG_HUMAN (701-1075): 0: 584: 90.93		GELS_HUMAN (2-715): 0: 1033: 59.86
+	Hs
		442287 ACTA_HUMAN (701-1075): 0: 579: 86.40		GELS_HUMAN (2-715): 0: 1033: 59.86
+	Hs
		442291 ACTC_HUMAN (701-1075): 0: 579: 86.67		GELS_HUMAN (2-715): 0: 1033: 59.86
+	Oc
		107639 ACTB_RABIT (701-1075): 0: 582: 91.20		G1U9R8_RABIT (2-715): 0: 1029: 59.86
+	Hs
		442292 ACTS_HUMAN (701-1075): 0: 578: 86.13		GELS_HUMAN (2-715): 0: 1033: 59.86
+	Hs
		952789 ACTB_HUMAN (701-1075): 0: 584: 91.47		FLII_HUMAN (6-713): 0: 741: 27.38
+	Hs
		993152 ACTG_HUMAN (701-1075): 0: 584: 90.93		FLII_HUMAN (6-713): 0: 741: 27.38
+	Hs
		995568 ACTC_HUMAN (701-1075): 0: 579: 86.67		FLII_HUMAN (6-713): 0: 741: 27.38
+	Dm
		534423 ACT1_DROME (702-1075): 0: 582: 89.84		QUAI_DROME (7-714): 0: 624: 23.26
+	Hs
		818730 ACTG_HUMAN (701-1075): 0: 584: 90.93		CAPG_HUMAN (398-710): 1.17e-108: 335: 29.46
+	Bt
		235269 ACTB_BOVIN (701-1075): 0: 584: 91.47		SVIL_BOVIN (21-347): 2.81e-32: 137: 21.47
+	Hs
		336383 ACTB_HUMAN (701-1075): 0: 584: 91.47		SVIL_HUMAN (21-347): 1.63e-31: 134: 21.73