HitPredict

Interactor 1: CAPG (P40121)
Macrophage-capping protein (Actin regulatory protein CAP-G)
Gene: CAPG

Interactor 2: ACTG (P63261)
Actin, cytoplasmic 2 (EC 3.6.4.-) (Gamma-actin) [Cleaved into: Actin, cytoplasmic 2, N-terminally processed]
Gene: ACTG1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	39349928
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Actin~Gelsolin
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0015629 - actin cytoskeleton GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 348 Hs			1 375
+	Hs
		1201102 SCIN_HUMAN (4-347): 5.1e-71: 236: 28.53		ACTBL_HUMAN (2-375): 0: 734: 91.44
+	Hs
		442347 GELS_HUMAN (14-347): 2.02e-68: 230: 27.99		ACTBL_HUMAN (2-375): 0: 734: 91.44
+	Hs
		953222 SCIN_HUMAN (4-347): 5.1e-71: 236: 28.53		ACTB_HUMAN (1-375): 0: 604: 98.93
+	Hs
		993410 SCIN_HUMAN (4-347): 5.1e-71: 236: 28.53		ACTG_HUMAN (1-375): 0: 604: 100.00
+	Hs
		442280 GELS_HUMAN (14-347): 2.02e-68: 230: 27.99		ACTB_HUMAN (1-375): 0: 604: 98.93
+	Hs
		442290 GELS_HUMAN (14-347): 2.02e-68: 230: 27.99		ACTG_HUMAN (1-375): 0: 604: 100.00
+	Hs
		977870 SCIN_HUMAN (4-347): 5.1e-71: 236: 28.53		ACTA_HUMAN (2-375): 0: 594: 94.39
+	Hs
		995924 SCIN_HUMAN (4-347): 5.1e-71: 236: 28.53		ACTC_HUMAN (2-375): 0: 594: 94.39
+	Hs
		996568 SCIN_HUMAN (4-347): 5.1e-71: 236: 28.53		ACTS_HUMAN (2-375): 0: 594: 93.85
+	Oc
		107639 G1U9R8_RABIT (14-347): 1.33e-67: 227: 27.70		ACTB_RABIT (1-375): 0: 602: 98.67
+	Hs
		442287 GELS_HUMAN (14-347): 2.02e-68: 230: 27.99		ACTA_HUMAN (2-375): 0: 594: 94.39
+	Hs
		442291 GELS_HUMAN (14-347): 2.02e-68: 230: 27.99		ACTC_HUMAN (2-375): 0: 594: 94.39
+	Hs
		442292 GELS_HUMAN (14-347): 2.02e-68: 230: 27.99		ACTS_HUMAN (2-375): 0: 594: 93.85
+	Bt
		235269 SVIL_BOVIN (23-348): 1.03e-44: 166: 20.00		ACTB_BOVIN (1-375): 0: 604: 98.93
+	Hs
		336383 SVIL_HUMAN (23-348): 1.28e-43: 162: 19.53		ACTB_HUMAN (1-375): 0: 604: 98.93
+	Hs
		952789 FLII_HUMAN (20-347): 1.26e-29: 122: 18.85		ACTB_HUMAN (1-375): 0: 604: 98.93
+	Hs
		993152 FLII_HUMAN (20-347): 1.26e-29: 122: 18.85		ACTG_HUMAN (1-375): 0: 604: 100.00
+	Hs
		995568 FLII_HUMAN (20-347): 1.26e-29: 122: 18.85		ACTC_HUMAN (2-375): 0: 594: 94.39
+	Dm
		1014433 FLII_DROME (26-347): 6.57e-29: 119: 20.22		ACT6_DROME (2-375): 0: 596: 95.46
+	Dm
		534423 QUAI_DROME (6-348): 4.02e-23: 102: 16.67		ACT1_DROME (2-375): 0: 600: 98.13