HitPredict

Interactor 1: RAB4A (P20338)
Ras-related protein Rab-4A (EC 3.6.5.2)
Gene: RAB4A

Interactor 2: RAB1A (P62820)
Ras-related protein Rab-1A (EC 3.6.5.2) (YPT1-related protein)
Gene: RAB1A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~Ras
Common GO terms	GO:0003924 - GTPase activity GO:0003925 - G protein activity GO:0005525 - GTP binding GO:0016192 - vesicle-mediated transport GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 218 Hs			1 205
+	Hs
		956239 RAB2A_HUMAN (10-197): 4.01e-95: 278: 56.92		RAB1A_HUMAN (1-205): 2.5e-92: 270: 100.00
+	Mm
		937157 RAB8B_MOUSE (6-205): 1.07e-90: 266: 42.00		RAB8A_MOUSE (4-201): 2.64e-95: 277: 54.00
+	Hs
		956434 RAB2A_HUMAN (10-197): 4.01e-95: 278: 56.92		RAB8B_HUMAN (4-203): 4.05e-88: 259: 52.00
+	Hs
		956483 RAB2A_HUMAN (10-197): 4.01e-95: 278: 56.92		RAB1B_HUMAN (4-205): 1.62e-86: 255: 92.57
+	Hs
		956433 RAB2A_HUMAN (10-197): 4.01e-95: 278: 56.92		RAB1C_HUMAN (4-205): 1.76e-83: 247: 88.12
+	Hs
		981254 RAB1A_HUMAN (3-218): 1.74e-85: 253: 38.43		RAB1A_HUMAN (1-205): 2.5e-92: 270: 100.00
+	Hs
		1370778 RAB8B_HUMAN (6-205): 3.4e-90: 265: 42.00		RAB1B_HUMAN (4-205): 1.62e-86: 255: 92.57
+	Hs
		956233 RAB2A_HUMAN (10-197): 4.01e-95: 278: 56.92		RAB14_HUMAN (1-205): 9.34e-81: 241: 41.86
+	Dm
		197334 Q7KY04_DROME (6-216): 6.45e-92: 270: 77.25		O18335_DROME (1-205): 1.36e-81: 243: 45.07
+	Mm
		940538 RAB4A_MOUSE (1-218): 3.19e-86: 255: 97.71		RAB1B_MOUSE (4-205): 2.87e-86: 254: 91.58
+	Hs
		981357 RAB1A_HUMAN (3-218): 1.74e-85: 253: 38.43		RAB1B_HUMAN (4-205): 1.62e-86: 255: 92.57
+	Hs
		955985 RAB8B_HUMAN (6-205): 3.4e-90: 265: 42.00		RAB8A_HUMAN (4-203): 2.8e-81: 242: 54.00
+	Mm
		981416 RAB1A_MOUSE (3-218): 1.74e-85: 253: 38.43		RAB1B_MOUSE (4-205): 2.87e-86: 254: 91.58
+	Hs
		957988 RAB8B_HUMAN (6-205): 3.4e-90: 265: 42.00		RAB14_HUMAN (1-205): 9.34e-81: 241: 41.86
+	Hs
		630753 RAB4A_HUMAN (1-218): 3.71e-86: 255: 100.00		RB11A_HUMAN (1-205): 5.36e-83: 247: 44.60
+	Hs
		976188 RAB1A_HUMAN (3-218): 1.74e-85: 253: 38.43		RB11A_HUMAN (1-205): 5.36e-83: 247: 44.60
+	Hs
		630748 RAB4A_HUMAN (1-218): 3.71e-86: 255: 100.00		RAB14_HUMAN (1-205): 9.34e-81: 241: 41.86
+	Hs
		981287 RAB1A_HUMAN (3-218): 1.74e-85: 253: 38.43		RB11B_HUMAN (1-205): 1.04e-81: 243: 44.19
+	Hs
		955910 RAB1A_HUMAN (3-218): 1.74e-85: 253: 38.43		RAB8A_HUMAN (4-203): 2.8e-81: 242: 54.00
+	Hs
		957907 RAB1A_HUMAN (3-218): 1.74e-85: 253: 38.43		RAB14_HUMAN (1-205): 9.34e-81: 241: 41.86