HitPredict

Interactor 1: BRM (P25439)
ATP-dependent helicase brm (EC 3.6.4.12) (Homeotic gene regulator) (Protein brahma)
Gene: BRM

Interactor 2: MED15 (Q9Y149)
Mediator of RNA polymerase II transcription subunit 15 (Mediator complex subunit 15) (dARC105)
Gene: MED15

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22036573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1638 Dm			1 749
+	Hs
		229378 SMCA5_HUMAN (621-1571): 0: 828: 28.82		BPTF_HUMAN (75-488): 1.42e-14: 80.4: 12.85
+	Hs
		658659 SMCA1_HUMAN (666-1571): 0: 820: 30.03		BPTF_HUMAN (75-488): 1.42e-14: 80.4: 12.85
+	Hs
		998717 CHD4_HUMAN (403-1599): 0: 783: 21.77		EP300_HUMAN (33-535): 1.45e-16: 86.6: 12.89
+	Hs
		1017295 CHD4_HUMAN (403-1599): 0: 783: 21.77		BPTF_HUMAN (75-488): 1.42e-14: 80.4: 12.85
+	Hs
		998619 CHD3_HUMAN (392-1632): 0: 776: 22.27		EP300_HUMAN (33-535): 1.45e-16: 86.6: 12.89
+	Hs
		1017286 CHD3_HUMAN (392-1632): 0: 776: 22.27		BPTF_HUMAN (75-488): 1.42e-14: 80.4: 12.85
+	Hs
		1336298 CHD8_HUMAN (15-1550): 0: 768: 20.25		CHD7_HUMAN (61-597): 1.04e-16: 87.3: 12.37
+	Hs
		1018618 CHD3_HUMAN (392-1632): 0: 776: 22.27		CBP_HUMAN (136-522): 8.25e-13: 74.6: 15.25
+	Hs
		1059674 CHD4_HUMAN (403-1599): 0: 783: 21.77		ADNP2_HUMAN (163-564): 2.61e-10: 66.2: 11.88
+	Hs
		1017327 CHD5_HUMAN (403-1636): 0: 767: 20.74		BPTF_HUMAN (75-488): 1.42e-14: 80.4: 12.85
+	Hs
		867130 CHD8_HUMAN (15-1550): 0: 768: 20.25		SC24C_HUMAN (69-344): 5.22e-12: 71.6: 15.00
+	Hs
		1153496 CHD5_HUMAN (403-1636): 0: 767: 20.74		ADNP2_HUMAN (163-564): 2.61e-10: 66.2: 11.88
+	Hs
		847103 SMCA4_HUMAN (182-732): 3.64e-11: 70.5: 9.57		CHD7_HUMAN (61-597): 1.04e-16: 87.3: 12.37
+	Hs
		846947 SMCA4_HUMAN (182-732): 3.64e-11: 70.5: 9.57		EP300_HUMAN (33-535): 1.45e-16: 86.6: 12.89
+	Mm
		57185 SMCA4_MOUSE (1-317): 9.99e-14: 79: 18.07		CHD7_MOUSE (61-501): 1.76e-13: 76.9: 12.04
+	Hs
		846760 SMCA2_HUMAN (231-741): 9.52e-09: 62.8: 10.17		EP300_HUMAN (33-535): 1.45e-16: 86.6: 12.89
+	Hs
		847041 SMCA4_HUMAN (182-732): 3.64e-11: 70.5: 9.57		CBP_HUMAN (136-522): 8.25e-13: 74.6: 15.25
+	Hs
		846837 SMCA2_HUMAN (231-741): 9.52e-09: 62.8: 10.17		CBP_HUMAN (136-522): 8.25e-13: 74.6: 15.25