Protein: SYNE1
Nesprin-1 (Enaptin) (KASH domain-containing protein 1) (KASH1) (Myocyte nuclear envelope protein 1) (Myne-1) (Nuclear envelope spectrin repeat protein 1) (Synaptic nuclear envelope protein 1) (Syne-1)

Gene: SYNE1
Organism: Homo sapiens
Interactions: 111
UniProt ID: Q8NF91

Gene Ontology (top 5):
GO:0000932 - P-body
GO:0002053 - positive regulation of mesenchymal cell proliferation
GO:0003723 - RNA binding
GO:0003779 - actin binding
GO:0005102 - signaling receptor binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1244142

SUN2
SUN domain-containing protein 2

3

12

Small-scale

0.892

High

299693

SUN1
SUN domain-containing protein 1

2

12

Small-scale

0.831

High

1244115

SYNE1
Nesprin-1

1

16

Small-scale

0.740

High

169189

MUSK
Muscle, skeletal receptor tyrosine-protein kinase

1

14

Small-scale

0.713

High

234551

DSCAM
Cell adhesion molecule DSCAM

1

6

High-throughput

0.698

High

852393

MYOM1
Myomesin-1

1

7

High-throughput

0.698

High

156618

PPE1
Serine/threonine-protein phosphatase with EF-hands 1

1

11

High-throughput

0.691

High

838991

EMD
Emerin

3

4

Small-scale

0.675

High

1244138

DISC1
Disrupted in schizophrenia 1 protein

3

9

Small-scale

0.667

High

1244141

IFT57
Intraflagellar transport protein 57 homolog

3

0

High-throughput

0.638

High

360179

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

2

13

Small-scale

0.624

High

385192

NTRK1
High affinity nerve growth factor receptor

1

15

High-throughput

0.618

High

981895

RON
Macrophage-stimulating protein receptor

1

20

High-throughput

0.618

High

1170890

TRI67
Tripartite motif-containing protein 67

1

12

High-throughput

0.618

High

1080128

EZH2
Histone-lysine N-methyltransferase EZH2

2

6

High-throughput

0.601

High

225243

3BP5
SH3 domain-binding protein 5

2

3

High-throughput

0.576

High

1244128

CDC5L
Cell division cycle 5-like protein

2

8

High-throughput

0.576

High

1244144

TNIK
TRAF2 and NCK-interacting protein kinase

2

20

High-throughput

0.576

High

1244119

SYNE2
Nesprin-2

1

16

Small-scale

0.575

High

370043

ESR1
Estrogen receptor

2

18

High-throughput

0.571

High

718032

BMI1
Polycomb complex protein BMI-1

2

15

High-throughput

0.571

High

600623

EPHA1
Ephrin type-A receptor 1

1

6

High-throughput

0.553

High

317303

PCNT
Pericentrin

1

20

High-throughput

0.541

High

626202

APC
Adenomatous polyposis coli protein

1

13

High-throughput

0.541

High

673760

BKRB2
B2 bradykinin receptor

1

4

High-throughput

0.541

High

894227

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.541

High

1078871

ITSN1
Intersectin-1

1

14

High-throughput

0.541

High

1244126

PRPK
EKC/KEOPS complex subunit TP53RK

1

10

High-throughput

0.541

High

1030366

G3BP1
Ras GTPase-activating protein-binding protein 1

1

2

High-throughput

0.536

High

1244124

CEP63
Centrosomal protein of 63 kDa

2

20

High-throughput

0.526

High

1244133

NDEL1
Nuclear distribution protein nudE-like 1

2

20

High-throughput

0.526

High

1051178

BTG3
Protein BTG3

1

0

High-throughput

0.518

High

398916

HMGN2
Non-histone chromosomal protein HMG-17

1

1

High-throughput

0.515

High

559182

H15
Histone H1.5

1

3

High-throughput

0.515

High

1132598

AXDN1
Axonemal dynein light chain domain-containing protein 1

1

1

High-throughput

0.515

High

1244147

TNF18
Tumor necrosis factor ligand superfamily member 18

1

0

High-throughput

0.513

High

957740

XIAP
E3 ubiquitin-protein ligase XIAP

1

5

High-throughput

0.501

High

1244120

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

8

High-throughput

0.501

High

1244131

DDX23
Probable ATP-dependent RNA helicase DDX23

1

0

High-throughput

0.493

High

661359

S10A2
Protein S100-A2

1

3

High-throughput

0.489

High

1139403

ECM29
Proteasome adapter and scaffold protein ECM29

1

1

Small-scale

0.481

High

1244122

DTBP1
Dysbindin

1

5

High-throughput

0.481

High

1244143

UBP21
Ubiquitin carboxyl-terminal hydrolase 21

1

4

Small-scale

0.481

High

149072

CTRO
Citron Rho-interacting kinase

1

12

High-throughput

0.479

High

151094

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

11

High-throughput

0.479

High

210137

PRC1
Protein regulator of cytokinesis 1

1

16

High-throughput

0.479

High

255932

OBSL1
Obscurin-like protein 1

1

19

High-throughput

0.479

High

308902

KI20A
Kinesin-like protein KIF20A

1

20

High-throughput

0.479

High

322899

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

5

High-throughput

0.479

High

379631

MYCN
N-myc proto-oncogene protein

1

10

High-throughput

0.479

High

391033

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

4

High-throughput

0.479

High

422424

NFM
Neurofilament medium polypeptide

1

18

High-throughput

0.479

High

531912

PDIA4
Protein disulfide-isomerase A4

1

7

High-throughput

0.479

High

591939

RAB4A
Ras-related protein Rab-4A

1

10

High-throughput

0.479

High

795203

SSRA
Translocon-associated protein subunit alpha

1

3

High-throughput

0.479

High

807779

MAP1B
Microtubule-associated protein 1B

1

18

High-throughput

0.479

High

832590

MCM2
DNA replication licensing factor MCM2

1

6

High-throughput

0.479

High

842960

TCPQ
T-complex protein 1 subunit theta

1

2

High-throughput

0.479

High

884542

RAB25
Ras-related protein Rab-25

1

4

High-throughput

0.479

High

884762

NU107
Nuclear pore complex protein Nup107

1

1

High-throughput

0.479

High

890275

SC61B
Protein transport protein Sec61 subunit beta

1

2

High-throughput

0.479

High

897184

TM258
Transmembrane protein 258

1

3

Small-scale

0.479

High

908843

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

6

High-throughput

0.479

High

935005

H31
Histone H3.1

1

7

High-throughput

0.479

High

1017716

STX4
Syntaxin-4

1

8

High-throughput

0.479

High

1035903

BIRC3
Baculoviral IAP repeat-containing protein 3

1

4

High-throughput

0.479

High

1042079

CUL3
Cullin-3

1

8

High-throughput

0.479

High

1054446

RBM39
RNA-binding protein 39

1

3

High-throughput

0.479

High

1063500

SUZ12
Polycomb protein SUZ12

1

1

High-throughput

0.479

High

1063961

TNIP1
TNFAIP3-interacting protein 1

1

20

High-throughput

0.479

High

1074183

SF3A1
Splicing factor 3A subunit 1

1

1

High-throughput

0.479

High

1074948

TERF2
Telomeric repeat-binding factor 2

1

10

High-throughput

0.479

High

1085836

IF16
Gamma-interferon-inducible protein 16

1

1

High-throughput

0.479

High

1137099

CROCC
Rootletin

1

20

Small-scale

0.479

High

1220598

MIRO2
Mitochondrial Rho GTPase 2

1

20

High-throughput

0.479

High

1240211

DHB11
Estradiol 17-beta-dehydrogenase 11

1

3

High-throughput

0.479

High

1244118

NUDC2
NudC domain-containing protein 2

1

5

High-throughput

0.479

High

1244121

LRC59
Leucine-rich repeat-containing protein 59

1

4

High-throughput

0.479

High

1244123

DNJC1
DnaJ homolog subfamily C member 1

1

13

High-throughput

0.479

High

1244127

SEC62
Translocation protein SEC62

1

3

High-throughput

0.479

High

1244129

RING2
E3 ubiquitin-protein ligase RING2

1

18

High-throughput

0.479

High

1244132

LNP
Endoplasmic reticulum junction formation protein lunapark

1

2

High-throughput

0.479

High

1244135

GAN
Gigaxonin

1

9

High-throughput

0.479

High

1244136

TMT1A
Thiol S-methyltransferase TMT1A

1

3

High-throughput

0.479

High

1244137

ANLN
Anillin

1

9

High-throughput

0.479

High

1244148

TRRAP
Transformation/transcription domain-associated protein

1

6

High-throughput

0.479

High

1244150

HEY1
Hairy/enhancer-of-split related with YRPW motif protein 1

1

3

Small-scale

0.479

High

1244151

MTCH2
Mitochondrial carrier homolog 2

1

1

High-throughput

0.479

High

948893

SARNP
SAP domain-containing ribonucleoprotein

1

0

High-throughput

0.458

High

1244116

NUP35
Nucleoporin NUP35

1

0

High-throughput

0.458

High

1244125

MUS81
Crossover junction endonuclease MUS81

1

0

High-throughput

0.458

High

1244140

PANK4
4'-phosphopantetheine phosphatase

1

0

High-throughput

0.458

High

1244149

PPME1
Protein phosphatase methylesterase 1

1

0

Small-scale

0.458

High

1244139

EXOC1
Exocyst complex component 1

1

4

High-throughput

0.457

High

240102

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

8

High-throughput

0.445

High

347372

MYC
Myc proto-oncogene protein

1

10

High-throughput

0.445

High

1043970

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

9

High-throughput

0.445

High

1233109

RYBP
RING1 and YY1-binding protein

1

2

High-throughput

0.445

High

1244145

AGO2
Protein argonaute-2

1

5

High-throughput

0.445

High

1244146

AGO1
Protein argonaute-1

1

5

High-throughput

0.445

High

129801

AGRIN
Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment

1

11

High-throughput

0.437

High

329847

AGR2
Anterior gradient protein 2 homolog

1

6

High-throughput

0.437

High

1040172

STIM1
Stromal interaction molecule 1

1

4

High-throughput

0.437

High

1048766

TRI29
Tripartite motif-containing protein 29

1

2

High-throughput

0.437

High

1230284

CXD3
Gap junction delta-3 protein

1

12

High-throughput

0.437

High

1244134

DJC25
DnaJ homolog subfamily C member 25

1

7

High-throughput

0.437

High

886306

DSCR9
Down syndrome critical region protein 9

1

3

High-throughput

0.417

High

1244117

MIPT3
TRAF3-interacting protein 1

1

6

High-throughput

0.417

High

1244130

MMP19
Matrix metalloproteinase-19

1

0

High-throughput

0.279

Low

1091138

WHAL1
Putative WASP homolog-associated protein with actin, membranes and microtubules-like protein 1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024