HitPredict

Interactor 1: RAB5A (P20339)
Ras-related protein Rab-5A (EC 3.6.5.2)
Gene: RAB5A

Interactor 2: SYNE2 (Q8WXH0)
Nesprin-2 (KASH domain-containing protein 2) (KASH2) (Nuclear envelope spectrin repeat protein 2) (Nucleus and actin connecting element protein) (Protein NUANCE) (Synaptic nuclear envelope protein 2) (Syne-2)
Gene: SYNE2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	34079125, unassigned3799
Identification Methods	proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0070062 - extracellular exosome
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 215 Hs			1 6885
+	Hs
		976454 RB11A_HUMAN (11-215): 2.1e-82: 245: 38.32		SYNE2_HUMAN (1-6885): 0: 1490: 100.00
+	Hs
		631414 RAB5A_HUMAN (1-215): 2.08e-88: 260: 100.00		CLMN_HUMAN (18-283): 7.66e-50: 198: 47.06
+	Mm
		1190044 RAB5A_MOUSE (1-215): 7.29e-89: 262: 98.14		Q3UGX2_MOUSE (5242-6811): 7.49e-22: 108: 10.54
+	Hs
		900777 RAB5C_HUMAN (1-215): 3.9e-85: 252: 86.57		SPTB2_HUMAN (5537-6835): 6.21e-24: 115: 9.45
+	Hs
		631180 RAB5A_HUMAN (1-215): 2.08e-88: 260: 100.00		DYST_HUMAN (5367-6840): 5.03e-21: 105: 10.19
+	Mm
		770492 RAB5C_MOUSE (1-215): 2.14e-85: 253: 86.57		Q3UGX2_MOUSE (5242-6811): 7.49e-22: 108: 10.54
+	Hs
		976210 RB11A_HUMAN (11-215): 2.1e-82: 245: 38.32		SPTB2_HUMAN (5537-6835): 6.21e-24: 115: 9.45
+	Hs
		976216 RB11A_HUMAN (11-215): 2.1e-82: 245: 38.32		DYST_HUMAN (5367-6840): 5.03e-21: 105: 10.19
+	Hs
		174724 RAB5C_HUMAN (1-215): 3.9e-85: 252: 86.57		SPTN2_HUMAN (3531-5279): 9.06e-16: 88.3: 8.43
+	Hs
		631565 RAB5A_HUMAN (1-215): 2.08e-88: 260: 100.00		MACF1_HUMAN (5906-6858): 3.06e-10: 70.2: 10.46