HitPredict

Interactor 1: VATL1 (P25515)
V-type proton ATPase subunit c (V-ATPase subunit c) (Guanine nucleotide exchange factor 2) (V-ATPase 16 kDa proteolipid subunit 1) (Vacuolar proton pump c subunit)
Gene: VMA3

Interactor 2: VATL1 (P25515)
V-type proton ATPase subunit c (V-ATPase subunit c) (Guanine nucleotide exchange factor 2) (V-ATPase 16 kDa proteolipid subunit 1) (Vacuolar proton pump c subunit)
Gene: VMA3

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	1.00	0.815

The method score is based on:

Property	Details
Experiments	18307317, 16093310, 12038966
Identification Methods	unspecified method, protein complementation assay, pull down
Interaction Type	direct interaction

The annotation score is based on:

Property	Details
Interacting Pfam domains	ATP-synt_C~ATP-synt_C
Common GO terms	GO:0000139 - Golgi membrane GO:0000220 - vacuolar proton-transporting V-type ATPase, V0 domain GO:0000329 - fungal-type vacuole membrane GO:0006623 - protein targeting to vacuole GO:0006878 - intracellular copper ion homeostasis and 12 others more... GO:0006879 - intracellular iron ion homeostasis GO:0006897 - endocytosis GO:0007033 - vacuole organization GO:0007035 - vacuolar acidification GO:0015078 - proton transmembrane transporter activity GO:0016020 - membrane GO:0016471 - vacuolar proton-transporting V-type ATPase complex GO:0033176 - proton-transporting V-type ATPase complex GO:0046961 - proton-transporting ATPase activity, rotational mechanism GO:0048388 - endosomal lumen acidification GO:0061795 - Golgi lumen acidification GO:1902600 - proton transmembrane transport
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1	160
Sc

1	160

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Last updated: 15 Jul 2024