Interactor 1: SPB1 (P25582)
27S pre-rRNA (guanosine(2922)-2'-O)-methyltransferase (EC 2.1.1.167) (2'-O-ribose RNA methyltransferase SPB1) (AdoMet-dependent rRNA methyltransferase SPB1) (S-adenosyl-L-methionine-dependent methyltransferase) (Suppressor of PAB1 protein 1)
Gene: SPB1

Interactor 2: NOP2 (P40991)
25S rRNA (cytosine(2870)-C(5))-methyltransferase (EC 2.1.1.310) (Nucleolar protein 2)
Gene: NOP2

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 0.60 0.640

The method score is based on:

Property Details
Experiments 34686661, 37968396, 37811893
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000463 - maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0005634 - nucleus
GO:0005730 - nucleolus
GO:0030687 - preribosome, large subunit precursor
GO:0031167 - rRNA methylation
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 841
Sc

1 618
+ Hs
+ Dm
+ Sc
+ Hs
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024