HitPredict

Interactor 1: MRC1 (P25588)
Mediator of replication checkpoint protein 1 (DNA replication checkpoint mediator MRC1)
Gene: MRC1

Interactor 2: MCM4 (P30665)
DNA replication licensing factor MCM4 (EC 3.6.4.12) (Cell division control protein 54)
Gene: MCM4

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.91	0.60	0.740

Property	Details
Experiments	25870112, 19620285, 26255844, 32075754, 19910927, 19661920, 22325992
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0031298 - replication fork protection complex GO:0043596 - nuclear replication fork
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 1096 Sc			1 933
+	Sc
		634888 MRC1_YEAST (1-1096): 0: 2005: 100.00		MCM6_YEAST (106-930): 0: 696: 23.84
+	Sc
		634862 MRC1_YEAST (1-1096): 0: 2005: 100.00		MCM5_YEAST (189-905): 0: 679: 26.92
+	Sc
		634861 MRC1_YEAST (1-1096): 0: 2005: 100.00		MCM2_YEAST (23-849): 0: 677: 25.49
+	Sc
		634876 MRC1_YEAST (1-1096): 0: 2005: 100.00		MCM7_YEAST (314-863): 6.73e-96: 322: 39.04