HitPredict

Interactor 1: STP22 (P25604)
Suppressor protein STP22 of temperature-sensitive alpha-factor receptor and arginine permease (ESCRT-I complex subunit VPS23) (Vacuolar protein sorting-associated protein 23)
Gene: STP22

Interactor 2: HSE1 (P38753)
Class E vacuolar protein-sorting machinery protein HSE1
Gene: HSE1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.76 0.60 0.676

The method score is based on:

Property Details
Experiments 11743162, 15086794, 19841731
Identification Methods two hybrid, peptide array, two hybrid array, two hybrid pooling approach
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005768 - endosome
GO:0006623 - protein targeting to vacuole
GO:0043130 - ubiquitin binding
GO:0043162 - ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
GO:0045324 - late endosome to vacuole transport
and 1 others

more...
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 385
Sc

1 452
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ At
+ At
+ Hs
+ Ce
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024