HitPredict

Interactor 1: IKBA (P25963)
NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkB-alpha) (IkappaBalpha) (Major histocompatibility complex enhancer-binding protein MAD3)
Gene: NFKBIA

Interactor 2: NU153 (P49790)
Nuclear pore complex protein Nup153 (153 kDa nucleoporin) (Nucleoporin Nup153)
Gene: NUP153

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	32912968
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0006606 - protein import into nucleus GO:0008139 - nuclear localization sequence binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 317 Hs			1 1475
+	Hs
		639698 IKBA_HUMAN (1-317): 2.59e-84: 258: 100.00		RBP2_HUMAN (573-1152): 6.9e-53: 207: 19.12
+	Dr
		47637 A0AR23_DANRE (6-314): 4.5e-70: 236: 21.61		ZRN1B_DANRE (589-768): 5.91e-26: 117: 18.14
+	Hs
		1071511 ANKR1_HUMAN (9-271): 4.53e-68: 217: 27.17		TITIN_HUMAN (92-940): 3.34e-30: 133: 9.98
+	Hs
		639794 IKBA_HUMAN (1-317): 2.59e-84: 258: 100.00		P121A_HUMAN (102-1074): 5.78e-16: 86: 9.24
+	Dr
		48763 MIB1_DANRE (1-299): 1.46e-66: 226: 24.63		ZRN1B_DANRE (589-768): 5.91e-26: 117: 18.14
+	Hs
		310053 TNKS1_HUMAN (187-313): 1.98e-30: 123: 18.75		MDC1_HUMAN (67-796): 3.59e-56: 217: 14.00
+	Hs
		1056981 TNKS2_HUMAN (187-313): 3.7e-30: 122: 17.97		MDC1_HUMAN (67-796): 3.59e-56: 217: 14.00
+	Hs
		961441 NFKB2_HUMAN (68-294): 6.66e-64: 218: 34.32		ZRAN1_HUMAN (589-796): 5.46e-22: 105: 16.89
+	Mm
		57587 ANKR1_MOUSE (12-280): 1.61e-64: 207: 26.20		TITIN_MOUSE (89-811): 1.42e-21: 104: 10.08
+	Hs
		1290067 TANC2_HUMAN (3-181): 3.02e-21: 96.6: 17.88		RNF31_HUMAN (545-922): 9.86e-47: 185: 15.72
+	Hs
		152793 MIB1_HUMAN (187-313): 7.22e-23: 101: 18.11		RGPD8_HUMAN (1136-1440): 1.82e-37: 156: 16.72
+	Hs
		257716 ANR17_HUMAN (20-307): 2.66e-38: 146: 13.27		ZRAN1_HUMAN (589-796): 5.46e-22: 105: 16.89
+	Dm
		1182373 Q7KU92_DROME (1-130): 3.34e-34: 134: 13.08		Q9VLS7_DROME (83-1183): 2.17e-23: 110: 9.02
+	Hs
		1021470 ANK3_HUMAN (1-130): 1.86e-30: 123: 10.77		ZRAN1_HUMAN (589-796): 5.46e-22: 105: 16.89
+	Dm
		1361443 Q9VAU5_DROME (171-314): 3.92e-27: 113: 16.35		Q9VLS7_DROME (83-1183): 2.17e-23: 110: 9.02
+	Hs
		556716 ANK1_HUMAN (224-317): 3.18e-13: 72.5: 14.85		TITIN_HUMAN (92-940): 3.34e-30: 133: 9.98
+	Hs
		166985 ANR28_HUMAN (3-94): 1.78e-12: 69.8: 7.45		TITIN_HUMAN (92-940): 3.34e-30: 133: 9.98
+	Hs
		587738 NFKB1_HUMAN (31-196): 3.47e-20: 93.1: 23.35		ZRAN1_HUMAN (589-796): 5.46e-22: 105: 16.89
+	Hs
		1219863 ANKH1_HUMAN (4-107): 2.55e-18: 87.9: 6.73		ZRAN1_HUMAN (589-796): 5.46e-22: 105: 16.89
+	Dm
		1362722 ANKHM_DROME (4-103): 3.34e-15: 78.3: 11.00		Q9VLS7_DROME (83-1183): 2.17e-23: 110: 9.02