HitPredict

Interactor 1: IKBA (P25963)
NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkB-alpha) (IkappaBalpha) (Major histocompatibility complex enhancer-binding protein MAD3)
Gene: NFKBIA

Interactor 2: PTN13 (Q12923)
Tyrosine-protein phosphatase non-receptor type 13 (EC 3.1.3.48) (Fas-associated protein-tyrosine phosphatase 1) (FAP-1) (PTP-BAS) (Protein-tyrosine phosphatase 1E) (PTP-E1) (hPTPE1) (Protein-tyrosine phosphatase PTPL1)
Gene: PTPN13

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.60	0.680

Property	Details
Experiments	9882613, 32912968, 11106428, 14743216
Identification Methods	pull down, affinity chromatography technology, tandem affinity purification
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 317 Hs			1 2485
+	Hs
		1020190 MIB1_HUMAN (187-313): 7.22e-23: 101: 18.11		PTN13_HUMAN (1-2485): 0: 1895: 100.00
+	Hs
		1020221 TANC2_HUMAN (3-181): 3.02e-21: 96.6: 17.88		PTN13_HUMAN (1-2485): 0: 1895: 100.00
+	Hs
		257705 ANR17_HUMAN (20-307): 2.66e-38: 146: 13.27		E41L5_HUMAN (513-1220): 6.79e-115: 385: 16.35
+	Hs
		719429 RIPK4_HUMAN (136-316): 6.43e-34: 133: 24.31		MERL_HUMAN (558-1049): 1.41e-117: 388: 23.65
+	Hs
		719616 Q9H4D1_HUMAN (136-316): 1.24e-33: 132: 24.31		MERL_HUMAN (558-1049): 1.41e-117: 388: 23.65
+	Hs
		1206062 MIB1_HUMAN (187-313): 7.22e-23: 101: 18.11		E41L5_HUMAN (513-1220): 6.79e-115: 385: 16.35
+	Hs
		1219853 ANKH1_HUMAN (4-107): 2.55e-18: 87.9: 6.73		E41L5_HUMAN (513-1220): 6.79e-115: 385: 16.35
+	Hs
		796421 ANKH1_HUMAN (4-107): 2.55e-18: 87.9: 6.73		PTN9_HUMAN (2136-2470): 4.76e-112: 372: 27.04
+	Hs
		577019 ANK3_HUMAN (1-130): 1.86e-30: 123: 10.77		PTPRA_HUMAN (2194-2468): 1.65e-96: 334: 31.10
+	Hs
		573574 IKBA_HUMAN (1-317): 2.59e-84: 258: 100.00		PTN1_HUMAN (2229-2465): 2.56e-45: 172: 37.40
+	Hs
		489900 NFKB1_HUMAN (31-196): 3.47e-20: 93.1: 23.35		PTPRF_HUMAN (2189-2468): 4.55e-89: 326: 30.38
+	Hs
		883516 RIPK4_HUMAN (136-316): 6.43e-34: 133: 24.31		PTPRK_HUMAN (2206-2470): 8.98e-55: 214: 23.83
+	Hs
		1069970 Q9H4D1_HUMAN (136-316): 1.24e-33: 132: 24.31		PTPRK_HUMAN (2206-2470): 8.98e-55: 214: 23.83
+	Hs
		1076940 ANR50_HUMAN (2-66): 2.02e-09: 60.6: 4.62		PTN14_HUMAN (553-1426): 3.67e-75: 277: 15.87
+	Hs
		570563 CSKI1_HUMAN (175-314): 1.19e-21: 97.7: 19.29		PTN2_HUMAN (2231-2465): 3.03e-45: 172: 37.50
+	Hs
		573970 KDIS_HUMAN (225-314): 1.26e-20: 94.5: 13.33		PTN1_HUMAN (2229-2465): 2.56e-45: 172: 37.40
+	Hs
		883551 RIPK4_HUMAN (136-316): 6.43e-34: 133: 24.31		MAGI2_HUMAN (873-1270): 1.19e-11: 72.9: 16.50
+	Hs
		1199790 Q9H4D1_HUMAN (136-316): 1.24e-33: 132: 24.31		MAGI2_HUMAN (873-1270): 1.19e-11: 72.9: 16.50
+	Hs
		640286 KDIS_HUMAN (225-314): 1.26e-20: 94.5: 13.33		PTN3_HUMAN (1207-1558): 1.58e-17: 91.9: 11.02
+	Hs
		640287 ANR50_HUMAN (2-66): 2.02e-09: 60.6: 4.62		PTN3_HUMAN (1207-1558): 1.58e-17: 91.9: 11.02