Protein: TAF1
Transcription initiation factor TFIID subunit 1 (EC 2.3.1.48) (TAFII-130) (TAFII-145) (TBP-associated factor 1) (TBP-associated factor 145 kDa)

Gene: TAF1
Organism: Saccharomyces cerevisiae S288C
Interactions: 162
UniProt ID: P46677

Gene Ontology (top 5):
GO:0003682 - chromatin binding
GO:0004402 - histone acetyltransferase activity
GO:0005634 - nucleus
GO:0005669 - transcription factor TFIID complex
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

561493

TBP
TATA-box-binding protein

32

8

Small-scale

0.993

High

858471

TAF7
Transcription initiation factor TFIID subunit 7

12

3

Small-scale

0.971

High

858430

TAF1
Transcription initiation factor TFIID subunit 1

3

2

Small-scale

0.817

High

858445

TAF6
SAGA complex/transcription factor TFIID complex subunit TAF6

20

3

Small-scale

0.765

High

858464

TAF12
SAGA complex/transcription factor TFIID complex subunit TAF12

18

5

Small-scale

0.763

High

793943

TAF5
SAGA complex/transcription factor TFIID complex subunit TAF5

18

6

Small-scale

0.763

High

858473

TAF9
SAGA complex/transcription factor TFIID complex subunit TAF9

16

3

Small-scale

0.761

High

858442

TAF4
Transcription initiation factor TFIID subunit 4

15

4

Small-scale

0.760

High

858482

TAF10
SAGA complex/transcription factor TFIID complex subunit TAF10

16

3

Small-scale

0.760

High

858468

TAF11
Transcription initiation factor TFIID subunit 11

15

2

Small-scale

0.758

High

655626

TAF2
Transcription initiation factor TFIID subunit 2

13

3

Small-scale

0.757

High

763343

TAF14
Transcription initiation factor TFIID subunit 14

13

1

Small-scale

0.754

High

548828

TAF13
Transcription initiation factor TFIID subunit 13

12

2

Small-scale

0.752

High

858486

TAF3
Transcription initiation factor TFIID subunit 3

16

0

Small-scale

0.728

High

858463

TAF8
Transcription initiation factor TFIID subunit 8

11

0

Small-scale

0.720

High

858457

ADA2
SAGA complex subunit ADA2

4

2

Small-scale

0.694

High

382181

H4
Histone H4

3

2

High-throughput

0.650

High

858487

RUVB2
RuvB-like protein 2

3

1

High-throughput

0.634

High

707462

TF2B
Transcription initiation factor IIB

3

0

Small-scale

0.613

High

777074

BDF1
Bromodomain-containing factor 1

2

13

Small-scale

0.612

High

452742

ADR1
Regulatory protein ADR1

2

1

Small-scale

0.611

High

638809

REB1
DNA-binding protein REB1

2

0

High-throughput

0.595

High

639032

VPS1
Vacuolar protein sorting-associated protein 1

2

0

High-throughput

0.595

High

733546

MED16
Mediator of RNA polymerase II transcription subunit 16

2

0

High-throughput

0.595

High

438313

NOT3
General negative regulator of transcription subunit 3

2

1

Small-scale

0.586

High

858489

NOT5
General negative regulator of transcription subunit 5

2

1

Small-scale

0.586

High

435186

RS3
Small ribosomal subunit protein uS3

2

0

High-throughput

0.585

High

689776

INO2
Protein INO2

2

0

Small-scale

0.577

High

381151

H2B1
Histone H2B.1

2

1

High-throughput

0.571

High

381551

H2B2
Histone H2B.2

2

1

High-throughput

0.571

High

794190

ISW1
ISWI chromatin-remodeling complex ATPase ISW1

2

3

High-throughput

0.571

High

858451

H3
Histone H3

2

5

High-throughput

0.571

High

678975

NOT1
General negative regulator of transcription subunit 1

1

0

Small-scale

0.568

High

477581

MYO1
Myosin-1

2

1

High-throughput

0.567

High

700067

FUN19
SWIRM domain-containing protein FUN19

2

0

High-throughput

0.563

High

858458

TBF1
Protein TBF1

2

0

High-throughput

0.563

High

858469

PUF6
Pumilio homology domain family member 6

2

0

High-throughput

0.563

High

807238

SPT8
SAGA complex subunit SPT8

2

0

Small-scale

0.560

High

858466

HMO1
High mobility group protein 1

1

2

Small-scale

0.552

High

550061

RAP1
DNA-binding protein RAP1

2

0

Small-scale

0.547

High

858460

GCN5
Histone acetyltransferase GCN5

1

7

High-throughput

0.536

High

545340

SSB1
Ribosome-associated molecular chaperone SSB1

2

0

High-throughput

0.528

High

858431

RS10B
Small ribosomal subunit protein eS10B

1

0

High-throughput

0.513

High

449458

SPT3
SAGA complex subunit SPT3

1

2

Small-scale

0.501

High

571297

DPOZ
DNA polymerase zeta catalytic subunit

1

0

High-throughput

0.493

High

805604

LSM12
Protein LSM12

1

0

High-throughput

0.493

High

547809

NHP6A
Non-histone chromosomal protein 6A

1

2

Small-scale

0.481

High

547878

NHP6B
Non-histone chromosomal protein 6B

1

2

Small-scale

0.481

High

823185

RAD26
DNA repair and recombination protein RAD26

1

4

High-throughput

0.481

High

858453

CTR9
RNA polymerase-associated protein CTR9

1

1

High-throughput

0.481

High

858478

IMH1
Golgin IMH1

1

3

High-throughput

0.481

High

858488

SKS1
Serine/threonine-protein kinase SKS1

1

1

High-throughput

0.481

High

858440

RFX1
RFX-like DNA-binding protein RFX1

1

0

Small-scale

0.480

High

858443

SPT20
SAGA complex subunit SPT20

1

0

Small-scale

0.480

High

504283

RL31A
Large ribosomal subunit protein eL31A

1

1

High-throughput

0.479

High

579626

HSC82
ATP-dependent molecular chaperone HSC82

1

1

High-throughput

0.479

High

736671

ASF1
Histone chaperone ASF1

1

1

Small-scale

0.479

High

858447

INO80
Chromatin-remodeling ATPase INO80

1

4

High-throughput

0.479

High

858449

APJ1
J domain-containing protein APJ1

1

1

High-throughput

0.479

High

597191

BIP
Endoplasmic reticulum chaperone BiP

1

0

High-throughput

0.460

High

676649

SGF29
SAGA complex subunit SGF29

1

0

High-throughput

0.460

High

704621

SBA1
Co-chaperone protein SBA1

1

0

Small-scale

0.460

High

736998

CDC3
Cell division control protein 3

1

0

High-throughput

0.460

High

751268

CNS1
Hsp70/Hsp90 co-chaperone CNS1

1

0

Small-scale

0.460

High

812430

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.460

High

822997

ATAD2
ATPase histone chaperone YTA7

1

0

High-throughput

0.460

High

830132

NOP2
25S rRNA

1

0

High-throughput

0.460

High

858433

YJ41B
Transposon Ty4-J Gag-Pol polyprotein

1

0

High-throughput

0.460

High

858436

EAF6
Chromatin modification-related protein EAF6

1

0

High-throughput

0.460

High

858475

NKP2
Inner kinetochore subunit NKP2

1

0

High-throughput

0.460

High

858483

NOP53
Ribosome biogenesis protein NOP53

1

0

High-throughput

0.460

High

149833

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.458

High

383770

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.458

High

395252

GCN4
General control transcription factor GCN4

1

0

Small-scale

0.458

High

410205

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.458

High

433711

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.458

High

441987

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.458

High

455132

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.458

High

503116

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.458

High

512512

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.458

High

513084

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.458

High

514700

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

594437

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.458

High

674698

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

735043

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

753446

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.458

High

763931

SPT10
Protein SPT10

1

0

High-throughput

0.458

High

778397

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

802246

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.458

High

858438

HIR3
Histone transcription regulator 3

1

0

High-throughput

0.458

High

858448

SGF73
SAGA complex subunit SGF73

1

0

High-throughput

0.458

High

858455

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

858467

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

858484

RIO1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

524353

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

527011

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

743106

STH1
Nuclear protein STH1/NPS1

1

4

High-throughput

0.445

High

744579

T2AG
Transcription initiation factor IIA subunit 2

1

1

High-throughput

0.445

High

802097

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

1

High-throughput

0.445

High

803990

RSC30
Chromatin structure-remodeling complex protein RSC30

1

1

High-throughput

0.445

High

850539

RSC8
Chromatin structure-remodeling complex protein RSC8

1

2

High-throughput

0.445

High

858456

RSC4
Chromatin structure-remodeling complex subunit RSC4

1

13

High-throughput

0.445

High

858465

RUVB1
RuvB-like protein 1

1

1

High-throughput

0.445

High

858474

ARP9
Actin-like protein ARP9

1

1

High-throughput

0.445

High

858476

RSC2
Chromatin structure-remodeling complex subunit RSC2

1

10

High-throughput

0.445

High

858477

RSC3
Chromatin structure-remodeling complex protein RSC3

1

1

High-throughput

0.445

High

858479

BDF2
Bromodomain-containing factor 2

1

10

High-throughput

0.445

High

858481

ISW2
ISWI chromatin-remodeling complex ATPase ISW2

1

4

High-throughput

0.445

High

858490

H2AZ
Histone H2A.Z

1

1

High-throughput

0.445

High

753109

NIP80
Protein NIP100

1

2

High-throughput

0.439

High

858485

RUD3
GRIP domain-containing protein RUD3

1

2

High-throughput

0.439

High

403555

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

0

High-throughput

0.426

High

419787

H2A2
Histone H2A.2

1

0

High-throughput

0.426

High

432622

RL7A
Large ribosomal subunit protein uL30A

1

0

High-throughput

0.426

High

448187

HAP2
Transcriptional activator HAP2

1

0

High-throughput

0.426

High

453660

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.426

High

531792

RL4A
Large ribosomal subunit protein uL4A

1

0

High-throughput

0.426

High

534066

HSF
Heat shock transcription factor

1

0

High-throughput

0.426

High

569808

RL30
Large ribosomal subunit protein eL30

1

0

High-throughput

0.426

High

645458

XRN1
5'-3' exoribonuclease 1

1

0

High-throughput

0.426

High

664444

MCM3
DNA replication licensing factor MCM3

1

0

High-throughput

0.426

High

678331

RSC6
Chromatin structure-remodeling complex protein RSC6

1

0

High-throughput

0.426

High

684766

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.426

High

745597

RSC7
Chromatin structure-remodeling complex subunit RSC7

1

0

High-throughput

0.426

High

747443

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.426

High

754218

MSN4
Zinc finger protein MSN4

1

0

High-throughput

0.426

High

858446

MCM6
DNA replication licensing factor MCM6

1

0

High-throughput

0.426

High

858450

ACT
Actin

1

0

High-throughput

0.426

High

858454

CDC14
Tyrosine-protein phosphatase CDC14

1

0

High-throughput

0.426

High

427333

RLA0
Large ribosomal subunit protein uL10

1

1

High-throughput

0.407

High

858441

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

1

High-throughput

0.407

High

858472

RRP5
rRNA biogenesis protein RRP5

1

1

High-throughput

0.407

High

585305

FBRL
rRNA 2'-O-methyltransferase fibrillarin

2

0

High-throughput

0.307

High

780086

MNN4
Mannosyltransferase regulator 4

2

0

High-throughput

0.307

High

858461

CLU
Clustered mitochondria protein 1

2

0

High-throughput

0.307

High

154361

YO304
Uncharacterized protein YOR304C-A

1

0

High-throughput

0.251

Low

432015

ATPF
ATP synthase subunit 4, mitochondrial

1

0

High-throughput

0.251

Low

438211

CDC37
Hsp90 co-chaperone Cdc37

1

0

Small-scale

0.251

Low

723187

ATP7
ATP synthase subunit d, mitochondrial

1

0

High-throughput

0.251

Low

726577

VATC
V-type proton ATPase subunit C

1

0

High-throughput

0.251

Low

758108

CASP
Protein CASP

1

0

High-throughput

0.251

Low

776757

YKF0
Uncharacterized protein YKL050C

1

0

High-throughput

0.251

Low

780279

EBP2
rRNA-processing protein EBP2

1

0

High-throughput

0.251

Low

790451

PAM1
Protein PAM1

1

0

High-throughput

0.251

Low

797183

ATG14
Autophagy-related protein 14

1

0

High-throughput

0.251

Low

807899

BFR1
Nuclear segregation protein BFR1

1

0

High-throughput

0.251

Low

818370

VFA1
VPS4-associated protein 1

1

0

High-throughput

0.251

Low

858432

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.251

Low

858435

YJE9
Uncharacterized protein YJL049W

1

0

High-throughput

0.251

Low

858437

ACF4
Assembly-complementing factor 4

1

0

High-throughput

0.251

Low

858439

CCM1
Mitochondrial 15S rRNA processing factor CCM1

1

0

High-throughput

0.251

Low

858444

PSP1
Protein PSP1

1

0

High-throughput

0.251

Low

858452

HSK3
DASH complex subunit HSK3

1

0

High-throughput

0.251

Low

858462

RCF1
Respiratory supercomplex factor 1, mitochondrial

1

0

High-throughput

0.251

Low

858470

GLU2B
Glucosidase 2 subunit beta

1

0

High-throughput

0.251

Low

858480

YET3
Endoplasmic reticulum transmembrane protein 3

1

0

High-throughput

0.251

Low

797215

SHE3
SWI5-dependent HO expression protein 3

1

0

High-throughput

0.249

Low

850372

IOC3
ISWI one complex protein 3

1

0

High-throughput

0.249

Low

752424

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.232

Low

858434

NET1
Nucleolar protein NET1

1

0

High-throughput

0.232

Low

858459

RSC9
Chromatin structure-remodeling complex subunit RSC9

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025