HitPredict

Interactor 1: IKBA (P25963)
NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkB-alpha) (IkappaBalpha) (Major histocompatibility complex enhancer-binding protein MAD3)
Gene: NFKBIA

Interactor 2: TIM50 (Q3ZCQ8)
Mitochondrial import inner membrane translocase subunit TIM50
Gene: TIMM50

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	32912968, 14743216
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 317 Hs			1 353
+	Hs
		121589 IKBE_HUMAN (3-315): 1.28e-74: 239: 32.10		TIM50_HUMAN (1-353): 4.22e-155: 441: 100.00
+	Hs
		961394 NFKB2_HUMAN (68-294): 6.66e-64: 218: 34.32		TIM50_HUMAN (1-353): 4.22e-155: 441: 100.00
+	Hs
		883523 RIPK4_HUMAN (136-316): 6.43e-34: 133: 24.31		TIM50_HUMAN (1-353): 4.22e-155: 441: 100.00
+	Hs
		1114355 Q9H4D1_HUMAN (136-316): 1.24e-33: 132: 24.31		TIM50_HUMAN (1-353): 4.22e-155: 441: 100.00
+	Hs
		1076364 IKBB_HUMAN (68-169): 5.17e-13: 70.8: 28.16		TIM50_HUMAN (1-353): 4.22e-155: 441: 100.00
+	Hs
		171211 ANK3_HUMAN (1-130): 1.86e-30: 123: 10.77		CTDSL_HUMAN (121-301): 5.87e-74: 231: 27.78