Protein: PAPOA
Poly(A) polymerase alpha (PAP-alpha) (EC 2.7.7.19) (Polynucleotide adenylyltransferase alpha)

Gene: PAPOA, PAPOLA
Organism: Homo sapiens
Interactions: 59
UniProt ID: P51003

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0003723 - RNA binding
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

899744

CPSF1
Cleavage and polyadenylation specificity factor subunit 1

2

4

Small-scale

0.585

High

899738

NEK4
Serine/threonine-protein kinase Nek4

1

0

High-throughput

0.513

High

899746

CIRBP
Cold-inducible RNA-binding protein

1

0

High-throughput

0.513

High

899764

AURKB
Aurora kinase B

1

0

High-throughput

0.513

High

899766

TGIF2
Homeobox protein TGIF2

1

0

High-throughput

0.513

High

899768

ANLN
Anillin

1

0

High-throughput

0.513

High

899773

RM42
Large ribosomal subunit protein mL42

1

0

High-throughput

0.513

High

899751

FIP1
Pre-mRNA 3'-end-processing factor FIP1

1

5

Small-scale

0.501

High

899761

SYMPK
Symplekin

1

2

Small-scale

0.500

High

899769

CPSF2
Cleavage and polyadenylation specificity factor subunit 2

1

8

Small-scale

0.500

High

899770

CPSF3
Cleavage and polyadenylation specificity factor subunit 3

1

8

Small-scale

0.500

High

899739

HSP72
Heat shock-related 70 kDa protein 2

1

0

High-throughput

0.493

High

899743

REL
Proto-oncogene c-Rel

1

0

High-throughput

0.493

High

899772

BACE2
Beta-secretase 2

1

1

High-throughput

0.489

High

899749

SMAD2
Mothers against decapentaplegic homolog 2

1

0

High-throughput

0.486

High

188220

HDAC3
Histone deacetylase 3

1

2

Small-scale

0.479

High

413435

P53
Cellular tumor antigen p53

1

1

High-throughput

0.479

High

694956

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

899745

HDAC1
Histone deacetylase 1

1

1

Small-scale

0.479

High

899750

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

2

Small-scale

0.479

High

899752

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.479

High

899755

SIR2
NAD-dependent protein deacetylase sirtuin-2

1

1

Small-scale

0.479

High

899762

HDA10
Polyamine deacetylase HDAC10

1

1

Small-scale

0.479

High

899763

SIR1
NAD-dependent protein deacetylase sirtuin-1

1

1

Small-scale

0.479

High

899765

RSRC1
Serine/Arginine-related protein 53

1

1

High-throughput

0.479

High

899767

PKHA4
Pleckstrin homology domain-containing family A member 4

1

2

High-throughput

0.479

High

128869

MEN1
Menin

1

0

High-throughput

0.458

High

228209

CPSF5
Cleavage and polyadenylation specificity factor subunit 5

1

0

Small-scale

0.458

High

241124

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

259645

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.458

High

385567

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.458

High

411601

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.458

High

515682

TPC2B
Trafficking protein particle complex subunit 2B

1

0

High-throughput

0.458

High

557965

XRCC6
X-ray repair cross-complementing protein 6

1

0

High-throughput

0.458

High

588231

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

711695

RABP2
Cellular retinoic acid-binding protein 2

1

0

High-throughput

0.458

High

716002

GNA11
Guanine nucleotide-binding protein subunit alpha-11

1

0

High-throughput

0.458

High

767724

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

830364

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

899740

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

899741

H2B1C
Histone H2B type 1-C/E/F/G/I

1

0

High-throughput

0.458

High

899742

ACTC
Actin, alpha cardiac muscle 1

1

0

High-throughput

0.458

High

899747

IMB1
Importin subunit beta-1

1

0

Small-scale

0.458

High

899753

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

0

High-throughput

0.458

High

899754

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

899756

YAF2
YY1-associated factor 2

1

0

High-throughput

0.458

High

899757

RHG24
Rho GTPase-activating protein 24

1

0

High-throughput

0.458

High

899758

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.458

High

899759

TOPB1
DNA topoisomerase 2-binding protein 1

1

0

High-throughput

0.458

High

899760

CBP
CREB-binding protein

1

0

Small-scale

0.458

High

899748

PCBP2
Poly(rC)-binding protein 2

1

1

Small-scale

0.445

High

330082

VENTX
Homeobox protein VENTX

1

0

High-throughput

0.426

High

446780

NPM
Nucleophosmin

1

0

Small-scale

0.426

High

116550

H7C5Q0
Arginine and serine rich coiled-coil 1

1

1

High-throughput

0.407

High

142312

PEX7
Peroxisomal targeting signal 2 receptor

1

3

High-throughput

0.407

High

346908

BAG2
BAG family molecular chaperone regulator 2

1

0

High-throughput

0.279

Low

387809

FIBB
Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]

1

0

High-throughput

0.279

Low

899771

WASC3
WASH complex subunit 3

1

0

High-throughput

0.279

Low

373841

RASN
GTPase NRas

1

0

High-throughput

0.269

Low


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Last updated: 11Aug2025