HitPredict

Interactor 1: IKBA (P25963)
NF-kappa-B inhibitor alpha (I-kappa-B-alpha) (IkB-alpha) (IkappaBalpha) (Major histocompatibility complex enhancer-binding protein MAD3)
Gene: NFKBIA

Interactor 2: TBA1A (Q71U36)
Tubulin alpha-1A chain (EC 3.6.5.-) (Alpha-tubulin 3) (Tubulin B-alpha-1) (Tubulin alpha-3 chain) [Cleaved into: Detyrosinated tubulin alpha-1A chain]
Gene: TUBA1A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	14743216
Identification Methods	tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank_2~Tubulin
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 317 Hs			1 451
+	Hs
		428027 IKBA_HUMAN (1-317): 2.59e-84: 258: 100.00		TBB5_HUMAN (1-439): 0: 695: 40.77
+	Hs
		121557 IKBE_HUMAN (3-315): 1.28e-74: 239: 32.10		TBB5_HUMAN (1-439): 0: 695: 40.77
+	Hs
		961401 NFKB2_HUMAN (68-294): 6.66e-64: 218: 34.32		TBA1A_HUMAN (1-440): 0: 713: 100.00
+	Hs
		428142 NFKB2_HUMAN (68-294): 6.66e-64: 218: 34.32		TBB5_HUMAN (1-439): 0: 695: 40.77
+	Hs
		862023 DAPK1_HUMAN (27-317): 1.12e-62: 216: 17.11		TBB4B_HUMAN (1-437): 0: 693: 40.50
+	Hs
		965128 ANK2_HUMAN (118-315): 9.61e-41: 153: 23.50		TBA1A_HUMAN (1-440): 0: 713: 100.00
+	Hs
		428145 ANK2_HUMAN (118-315): 9.61e-41: 153: 23.50		TBB5_HUMAN (1-439): 0: 695: 40.77
+	Hs
		883475 RIPK4_HUMAN (136-316): 6.43e-34: 133: 24.31		TBA1B_HUMAN (1-440): 0: 715: 99.55
+	Hs
		933351 Q9H4D1_HUMAN (136-316): 1.24e-33: 132: 24.31		TBA1B_HUMAN (1-440): 0: 715: 99.55
+	Hs
		428113 RIPK4_HUMAN (136-316): 6.43e-34: 133: 24.31		TBB5_HUMAN (1-439): 0: 695: 40.77
+	Hs
		428431 Q9H4D1_HUMAN (136-316): 1.24e-33: 132: 24.31		TBB5_HUMAN (1-439): 0: 695: 40.77
+	Hs
		883476 RIPK4_HUMAN (136-316): 6.43e-34: 133: 24.31		TBB4B_HUMAN (1-437): 0: 693: 40.50
+	Hs
		933974 Q9H4D1_HUMAN (136-316): 1.24e-33: 132: 24.31		TBB4B_HUMAN (1-437): 0: 693: 40.50
+	Hs
		587694 NFKB1_HUMAN (31-196): 3.47e-20: 93.1: 23.35		TBA1C_HUMAN (1-451): 0: 726: 98.00
+	Hs
		1175004 MIB1_HUMAN (187-313): 7.22e-23: 101: 18.11		TBA1A_HUMAN (1-440): 0: 713: 100.00
+	Hs
		587516 NFKB1_HUMAN (31-196): 3.47e-20: 93.1: 23.35		TBA4A_HUMAN (1-450): 0: 717: 96.00
+	Hs
		587515 NFKB1_HUMAN (31-196): 3.47e-20: 93.1: 23.35		TBA1B_HUMAN (1-440): 0: 715: 99.55
+	Hs
		587615 NFKB1_HUMAN (31-196): 3.47e-20: 93.1: 23.35		TBA1A_HUMAN (1-440): 0: 713: 100.00
+	Hs
		428013 NFKB1_HUMAN (31-196): 3.47e-20: 93.1: 23.35		TBB5_HUMAN (1-439): 0: 695: 40.77
+	Hs
		587517 NFKB1_HUMAN (31-196): 3.47e-20: 93.1: 23.35		TBB4B_HUMAN (1-437): 0: 693: 40.50