Interactor 1: VDAC1 (P21796)
Non-selective voltage-gated ion channel VDAC1 (Outer mitochondrial membrane protein porin 1) (Plasmalemmal porin) (Porin 31HL) (Porin 31HM) (Voltage-dependent anion-selective channel protein 1) (VDAC-1) (hVDAC1)
Gene: VDAC1

Interactor 2: HXK2 (P52789)
Hexokinase-2 (EC 2.7.1.1) (Hexokinase type II) (HK II) (Hexokinase-B) (Muscle form hexokinase)
Gene: HK2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.62 0.60 0.611

The method score is based on:

Property Details
Experiments 32021252, 35271311
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005524 - ATP binding
GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane
GO:0016020 - membrane
GO:1905091 - positive regulation of type 2 mitophagy
and 1 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 283
Hs

1 917
+ Hs
+ Rn
+ Hs
+ Hs
+ Mm
+ Rn
+ At

Service provided by Combinatics, Japan

Last updated: 11Aug2025