Interactor 1: HXK2 (P27881)
Hexokinase-2 (EC 2.7.1.1) (Hexokinase type II) (HK II) (Hexokinase-B)
Gene: Hk2

Interactor 2: VDAC1 (Q9Z2L0)
Non-selective voltage-gated ion channel VDAC1 (Outer mitochondrial membrane protein porin 1) (Voltage-dependent anion-selective channel protein 1) (VDAC-1) (rVDAC1)
Gene: VDAC1

Species: Rattus norvegicus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 0.60 0.500

The method score is based on:

Property Details
Experiments 22233811
Identification Methods anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005524 - ATP binding
GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane
GO:1905091 - positive regulation of type 2 mitophagy
GO:2000378 - negative regulation of reactive oxygen species metabolic process
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 917
Rn

1 283
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Rn
+ At

Service provided by Combinatics, Japan

Last updated: 11Aug2025