HitPredict

Interactor 1: ELAV4 (P26378)
ELAV-like protein 4 (Hu-antigen D) (HuD) (Paraneoplastic encephalomyelitis antigen HuD)
Gene: ELAVL4

Interactor 2: FBW1B (Q9UKB1)
F-box/WD repeat-containing protein 11 (F-box and WD repeats protein beta-TrCP2) (F-box/WD repeat-containing protein 1B) (Homologous to Slimb protein) (HOS)
Gene: FBXW11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005635 - nuclear envelope
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 385 Hs			1 542
+	Hs
		516733 PABP1_HUMAN (292-383): 7.71e-21: 96.3: 21.74		FBW1B_HUMAN (1-542): 9.69e-174: 503: 100.00
+	Hs
		1031492 PABP4_HUMAN (292-383): 1.1e-20: 95.9: 21.74		FBW1B_HUMAN (1-542): 9.69e-174: 503: 100.00
+	Hs
		1077532 ELAV1_HUMAN (122-215): 1.57e-15: 78.6: 32.98		FBW1B_HUMAN (1-542): 9.69e-174: 503: 100.00
+	Hs
		668448 RBMS1_HUMAN (49-247): 7.12e-25: 106: 34.78		FBW1A_HUMAN (26-542): 3.86e-155: 458: 84.59
+	Hs
		516754 PABP1_HUMAN (292-383): 7.71e-21: 96.3: 21.74		FBW1A_HUMAN (26-542): 3.86e-155: 458: 84.59
+	Hs
		1031501 PABP4_HUMAN (292-383): 1.1e-20: 95.9: 21.74		FBW1A_HUMAN (26-542): 3.86e-155: 458: 84.59
+	Hs
		1077542 ELAV1_HUMAN (122-215): 1.57e-15: 78.6: 32.98		FBW1A_HUMAN (26-542): 3.86e-155: 458: 84.59
+	Hs
		516438 PABP1_HUMAN (292-383): 7.71e-21: 96.3: 21.74		WDR5_HUMAN (80-265): 5.44e-16: 81.1: 11.92
+	Hs
		903196 PABP4_HUMAN (292-383): 1.1e-20: 95.9: 21.74		WDR5_HUMAN (80-265): 5.44e-16: 81.1: 11.92
+	Hs
		1077517 ELAV1_HUMAN (122-215): 1.57e-15: 78.6: 32.98		NLE1_HUMAN (125-224): 6.61e-09: 60.3: 6.00