HitPredict

Interactor 1: P85A (P26450)
Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha)
Gene: Pik3r1

Interactor 2: IL2RG (P34902)
Cytokine receptor common subunit gamma (Interleukin-2 receptor subunit gamma) (IL-2 receptor subunit gamma) (IL-2R subunit gamma) (IL-2RG) (gammaC) (p64) (CD antigen CD132)
Gene: IL2RG

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17952078
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0010628 - positive regulation of gene expression GO:0030183 - B cell differentiation
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 724 Mm			1 369
+	Hs
		548790 P85A_HUMAN (1-724): 0: 556: 94.35		CSF2R_HUMAN (41-335): 2.46e-55: 188: 18.77
+	Hs
		655284 P85A_HUMAN (1-724): 0: 556: 94.35		EPHA5_HUMAN (46-285): 1.12e-48: 178: 13.04
+	Mm
		540266 P85A_MOUSE (1-724): 0: 566: 100.00		EPOR_MOUSE (2-310): 9.5e-46: 165: 18.93
+	Hs
		655222 P85A_HUMAN (1-724): 0: 556: 94.35		EPHB2_HUMAN (13-315): 1.07e-47: 175: 10.84
+	Hs
		655380 P85A_HUMAN (1-724): 0: 556: 94.35		EPHA7_HUMAN (20-285): 4.03e-46: 170: 9.09
+	Hs
		655220 P85A_HUMAN (1-724): 0: 556: 94.35		EPHA3_HUMAN (25-288): 1.19e-43: 163: 11.79
+	Hs
		655375 P85A_HUMAN (1-724): 0: 556: 94.35		PTPRK_HUMAN (10-366): 4.23e-43: 162: 11.80
+	Hs
		655246 P85A_HUMAN (1-724): 0: 556: 94.35		IL6RB_HUMAN (50-258): 6.68e-43: 161: 21.01
+	Hs
		500948 P85A_HUMAN (1-724): 0: 556: 94.35		GHR_HUMAN (37-294): 2.89e-43: 160: 14.59
+	Hs
		655221 P85A_HUMAN (1-724): 0: 556: 94.35		EPHA8_HUMAN (37-272): 5e-42: 158: 10.80
+	Hs
		655285 P85A_HUMAN (1-724): 0: 556: 94.35		EPHA4_HUMAN (20-253): 2.71e-41: 156: 13.60
+	Hs
		581150 P85A_HUMAN (1-724): 0: 556: 94.35		EPOR_HUMAN (6-310): 1.59e-41: 153: 19.11
+	Hs
		540445 P85A_HUMAN (1-724): 0: 556: 94.35		IL2RB_HUMAN (59-310): 6.8e-35: 136: 18.05
+	Hs
		129252 P85B_HUMAN (4-719): 5.61e-156: 471: 57.10		EPHA5_HUMAN (46-285): 1.12e-48: 178: 13.04
+	Hs
		129211 P85B_HUMAN (4-719): 5.61e-156: 471: 57.10		EPHB2_HUMAN (13-315): 1.07e-47: 175: 10.84
+	Hs
		129209 P85B_HUMAN (4-719): 5.61e-156: 471: 57.10		EPHA3_HUMAN (25-288): 1.19e-43: 163: 11.79
+	Hs
		129180 P85B_HUMAN (4-719): 5.61e-156: 471: 57.10		GHR_HUMAN (37-294): 2.89e-43: 160: 14.59
+	Hs
		562513 P85A_HUMAN (1-724): 0: 556: 94.35		IL7RA_HUMAN (137-300): 1.47e-13: 73.7: 17.71
+	Hs
		129210 P85B_HUMAN (4-719): 5.61e-156: 471: 57.10		EPHA8_HUMAN (37-272): 5e-42: 158: 10.80
+	Hs
		655234 P85A_HUMAN (1-724): 0: 556: 94.35		IL3RB_HUMAN (56-257): 3.88e-12: 69.8: 19.37