HitPredict

Interactor 1: NKG2A (P26715)
NKG2-A/NKG2-B type II integral membrane protein (CD159 antigen-like family member A) (NK cell receptor A) (NKG2-A/B-activating NK receptor) (CD antigen CD159a)
Gene: KLRC1

Interactor 2: LRFN1 (Q9P244)
Leucine-rich repeat and fibronectin type III domain-containing protein 1 (Synaptic adhesion-like molecule 2)
Gene: LRFN1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	fn3~Lectin_C, LRR_8~Lectin_C
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 233 Hs			1 771
+	Hs
		59802 KLRG2_HUMAN (75-231): 3.26e-45: 157: 24.05		LRFN1_HUMAN (1-771): 1.42e-157: 478: 100.00
+	Hs
		1350024 CLC4A_HUMAN (34-231): 2.26e-41: 142: 16.81		LRFN1_HUMAN (1-771): 1.42e-157: 478: 100.00
+	Hs
		644597 NKG2A_HUMAN (1-233): 3.96e-72: 221: 100.00		AMGO1_HUMAN (33-387): 5.25e-73: 248: 26.02
+	Hs
		644626 NKG2A_HUMAN (1-233): 3.96e-72: 221: 100.00		LRIG1_HUMAN (2-261): 4.49e-34: 142: 20.56
+	Hs
		1100734 CL12B_HUMAN (113-231): 1.89e-44: 151: 31.01		LRIG3_HUMAN (2-580): 4.83e-39: 158: 14.45
+	Hs
		259512 CLC4A_HUMAN (34-231): 2.26e-41: 142: 16.81		LRRN2_HUMAN (33-516): 1.38e-42: 167: 17.87
+	Hs
		1100782 CL12B_HUMAN (113-231): 1.89e-44: 151: 31.01		LIGO1_HUMAN (1-233): 4.3e-39: 155: 25.74
+	Hs
		1166673 CLC4A_HUMAN (34-231): 2.26e-41: 142: 16.81		LRIG3_HUMAN (2-580): 4.83e-39: 158: 14.45
+	Hs
		1291088 CLC4A_HUMAN (34-231): 2.26e-41: 142: 16.81		LIGO1_HUMAN (1-233): 4.3e-39: 155: 25.74
+	Hs
		1100785 CL12B_HUMAN (113-231): 1.89e-44: 151: 31.01		LRIG1_HUMAN (2-261): 4.49e-34: 142: 20.56
+	Hs
		299565 CL12B_HUMAN (113-231): 1.89e-44: 151: 31.01		LRIG2_HUMAN (2-426): 1.47e-32: 137: 15.32
+	Hs
		299599 CLC4E_HUMAN (51-231): 2.31e-43: 147: 16.51		LRIG2_HUMAN (2-426): 1.47e-32: 137: 15.32
+	Hs
		1263883 CLC4D_HUMAN (53-232): 2.6e-40: 139: 15.24		LRIG1_HUMAN (2-261): 4.49e-34: 142: 20.56
+	Hs
		299573 CLC4D_HUMAN (53-232): 2.6e-40: 139: 15.24		LRIG2_HUMAN (2-426): 1.47e-32: 137: 15.32
+	Hs
		1268547 CLC4A_HUMAN (34-231): 2.26e-41: 142: 16.81		PXDN_HUMAN (166-771): 3.46e-30: 130: 10.81
+	Hs
		59798 KLRG2_HUMAN (75-231): 3.26e-45: 157: 24.05		LRC4B_HUMAN (2-161): 3.42e-25: 113: 17.84
+	Hs
		1240649 CLC1A_HUMAN (113-232): 4.15e-38: 135: 25.39		LRC4C_HUMAN (5-333): 4.31e-25: 112: 15.06
+	Hs
		1100794 CL12B_HUMAN (113-231): 1.89e-44: 151: 31.01		LRFN3_HUMAN (2-115): 6e-15: 80.8: 16.95
+	Hs
		1265939 CLC2B_HUMAN (80-233): 3.14e-40: 137: 25.64		LRFN3_HUMAN (2-115): 6e-15: 80.8: 16.95
+	Hs
		296667 CLC4D_HUMAN (53-232): 2.6e-40: 139: 15.24		SLIT2_HUMAN (34-296): 1.87e-13: 76.6: 24.72