HitPredict

Interactor 1: IL3RB (P26955)
Cytokine receptor common subunit beta (GM-CSF/IL-3/IL-5 receptor common beta subunit) (CD antigen CD131)
Gene: Csf2rb

Interactor 2: CISH (Q62225)
Cytokine-inducible SH2-containing protein (CIS) (CIS-1) (Suppressor of cytokine signaling) (SOCS)
Gene: CISH

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	7796808
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 896 Mm			1 257
+	Mm
		645935 IL3B2_MOUSE (1-877): 0: 666: 91.70		CISH_MOUSE (1-257): 4.78e-74: 227: 100.00
+	Hs
		433612 IL3RB_HUMAN (5-896): 0: 608: 55.51		LYN_HUMAN (6-252): 1.98e-49: 171: 14.57
+	Hs
		412051 IL3RB_HUMAN (5-896): 0: 608: 55.51		FYN_HUMAN (17-252): 7.56e-49: 170: 12.54
+	Hs
		181806 IL3RB_HUMAN (5-896): 0: 608: 55.51		SOCS1_HUMAN (59-257): 6.41e-44: 149: 28.36
+	Hs
		655234 IL3RB_HUMAN (5-896): 0: 608: 55.51		P85A_HUMAN (62-189): 5.55e-17: 82.2: 16.92
+	Hs
		645925 IL3RA_HUMAN (176-504): 2.21e-65: 226: 18.68		CISH_HUMAN (1-257): 1.73e-67: 211: 87.21
+	Hs
		924483 IL5RA_HUMAN (138-485): 1.43e-77: 260: 19.14		GRB2_HUMAN (34-217): 2.53e-41: 143: 15.84
+	Hs
		412028 IL3RA_HUMAN (176-504): 2.21e-65: 226: 18.68		FYN_HUMAN (17-252): 7.56e-49: 170: 12.54
+	Hs
		560479 PRLR_HUMAN (242-639): 2.31e-45: 175: 14.46		CISH_HUMAN (1-257): 1.73e-67: 211: 87.21
+	Hs
		645898 IL3RA_HUMAN (176-504): 2.21e-65: 226: 18.68		GRB2_HUMAN (34-217): 2.53e-41: 143: 15.84
+	Hs
		256850 IL4RA_HUMAN (236-895): 8.36e-51: 194: 17.14		SOCS5_HUMAN (59-256): 3.21e-49: 171: 26.50
+	Hs
		433507 TUTLB_HUMAN (257-885): 3.25e-43: 172: 10.46		YES_HUMAN (31-252): 2.04e-50: 174: 13.52
+	Hs
		442787 IL6RB_HUMAN (244-445): 4.15e-41: 165: 21.76		HCK_HUMAN (4-252): 1.03e-52: 180: 13.77
+	Hs
		434081 TUTLB_HUMAN (257-885): 3.25e-43: 172: 10.46		LYN_HUMAN (6-252): 1.98e-49: 171: 14.57
+	Hs
		146590 PRLR_HUMAN (242-639): 2.31e-45: 175: 14.46		SOCS2_HUMAN (48-257): 1.58e-50: 165: 40.48
+	Hs
		523211 TUTLB_HUMAN (257-885): 3.25e-43: 172: 10.46		SRC_HUMAN (17-251): 9.43e-47: 164: 14.19
+	Hs
		147385 PRLR_HUMAN (242-639): 2.31e-45: 175: 14.46		SOCS3_HUMAN (51-253): 6.82e-46: 154: 30.14
+	Hs
		147398 IL6RB_HUMAN (244-445): 4.15e-41: 165: 21.76		SOCS3_HUMAN (51-253): 6.82e-46: 154: 30.14
+	Hs
		682260 IL2RG_HUMAN (250-560): 1.12e-46: 173: 19.39		GRB2_HUMAN (34-217): 2.53e-41: 143: 15.84
+	Hs
		548790 CSF2R_HUMAN (168-485): 4.15e-67: 231: 15.16		P85A_HUMAN (62-189): 5.55e-17: 82.2: 16.92