HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: ARHGG (Q5VV41)
Rho guanine nucleotide exchange factor 16 (Ephexin-4)
Gene: ARHGEF16

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.697

Property	Details
Experiments	33961781, 36931259, 15161933, 28514442
Identification Methods	affinity chromatography technology, proximity labelling technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 709
+	Hs
		909662 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		ARHGG_HUMAN (1-709): 1.15e-165: 494: 100.00
+	Hs
		909489 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		ARHG5_HUMAN (21-706): 2.23e-107: 359: 27.87
+	Hs
		646839 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		ARHG5_HUMAN (21-706): 2.23e-107: 359: 27.87
+	Hs
		909781 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		ARHGJ_HUMAN (18-708): 1.68e-104: 338: 26.71
+	Hs
		909921 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		SPT13_HUMAN (68-628): 2.4e-101: 326: 16.58
+	Hs
		910068 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		ARHG4_HUMAN (35-649): 2.82e-99: 321: 16.07
+	Hs
		909717 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		FGD6_HUMAN (38-671): 5.47e-93: 318: 14.99
+	Mm
		926797 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		ARHG2_MOUSE (59-702): 4.21e-97: 323: 15.14
+	Hs
		909883 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		ARHG2_HUMAN (59-702): 1.75e-93: 313: 14.99
+	Hs
		909551 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		ARHG7_HUMAN (59-686): 2.22e-94: 311: 13.06
+	Hs
		647028 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		FGD6_HUMAN (38-671): 5.47e-93: 318: 14.99
+	Hs
		909491 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		AKP13_HUMAN (82-702): 2.13e-89: 308: 13.27
+	Hs
		647169 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		ARHG2_HUMAN (59-702): 1.75e-93: 313: 14.99
+	Mm
		910228 1433E_MOUSE (2-243): 1.31e-144: 406: 63.53		ARG28_MOUSE (42-669): 6.4e-88: 304: 13.91
+	Hs
		909803 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		ARG28_HUMAN (42-669): 1.3e-87: 303: 14.85
+	Hs
		646842 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		AKP13_HUMAN (82-702): 2.13e-89: 308: 13.27
+	Mm
		926776 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		ARG28_MOUSE (42-669): 6.4e-88: 304: 13.91
+	Hs
		647099 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		ARG28_HUMAN (42-669): 1.3e-87: 303: 14.85
+	Hs
		297126 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		PKHG5_HUMAN (276-571): 5.33e-12: 71.6: 25.60
+	Hs
		297119 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		PKHG5_HUMAN (276-571): 5.33e-12: 71.6: 25.60