Protein: MEIS2
Homeobox protein Meis2 (Meis1-related protein 1)

Gene: MEIS2
Organism: Homo sapiens
Interactions: 90
UniProt ID: O14770

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

163415

PBX1
Pre-B-cell leukemia transcription factor 1

9

19

Small-scale

0.972

High

163472

PBX4
Pre-B-cell leukemia transcription factor 4

5

19

High-throughput

0.926

High

163416

PBX2
Pre-B-cell leukemia transcription factor 2

4

19

High-throughput

0.892

High

163417

PBX3
Pre-B-cell leukemia transcription factor 3

4

19

High-throughput

0.892

High

137112

MEIS1
Homeobox protein Meis1

3

20

High-throughput

0.861

High

163402

LMX1B
LIM homeobox transcription factor 1-beta

3

19

High-throughput

0.861

High

163413

TLX1
T-cell leukemia homeobox protein 1

2

20

Small-scale

0.783

High

70954

NOTO
Homeobox protein notochord

2

20

High-throughput

0.783

High

163425

PO6F2
POU domain, class 6, transcription factor 2

2

6

High-throughput

0.783

High

163467

MEIS3
Homeobox protein Meis3

2

19

High-throughput

0.754

High

163400

MEIS2
Homeobox protein Meis2

1

19

High-throughput

0.698

High

163481

MB212
Protein mab-21-like 2

4

10

High-throughput

0.691

High

163430

MB211
Putative nucleotidyltransferase MAB21L1

3

10

High-throughput

0.667

High

163428

TBX2
T-box transcription factor TBX2

2

14

High-throughput

0.606

High

163429

CENPR
Centromere protein R

2

2

High-throughput

0.606

High

163465

CRBN
Protein cereblon

2

1

Small-scale

0.595

High

163420

PKNX1
Homeobox protein PKNOX1

1

19

Small-scale

0.590

High

163401

MS18B
Protein Mis18-beta

2

0

High-throughput

0.580

High

163407

SECR
Secretin

2

0

High-throughput

0.580

High

163432

PTK6
Protein-tyrosine kinase 6

2

0

High-throughput

0.580

High

163439

OBF1
POU domain class 2-associating factor 1

2

0

High-throughput

0.580

High

163459

SMIP6
Sperm microtubule inner protein 6

2

0

High-throughput

0.580

High

163468

VGLL1
Transcription cofactor vestigial-like protein 1

2

0

High-throughput

0.580

High

163471

RUSC1
AP-4 complex accessory subunit RUSC1

2

0

High-throughput

0.580

High

64743

ME3L1
Putative homeobox protein Meis3-like 1

1

18

High-throughput

0.575

High

163448

F222A
Protein FAM222A

2

5

High-throughput

0.574

High

163457

DAAF8
Dynein axonemal assembly factor 8

2

5

High-throughput

0.574

High

163463

CC120
Coiled-coil domain-containing protein 120

2

6

High-throughput

0.574

High

4764

A0A1B0GWI1
Coiled-coil domain containing 196

2

1

High-throughput

0.558

High

163409

ADA2C
Alpha-2C adrenergic receptor

2

2

High-throughput

0.553

High

163438

CART

2

1

High-throughput

0.553

High

163456

TRI42
Tripartite motif-containing protein 42

2

6

High-throughput

0.553

High

163462

F136A
Protein FAM136A

2

2

High-throughput

0.553

High

163470

NUP58
Nucleoporin p58/p45

2

3

High-throughput

0.553

High

163436

ZNHI3
Zinc finger HIT domain-containing protein 3

1

1

High-throughput

0.541

High

163461

RBPMS
RNA-binding protein with multiple splicing

1

0

High-throughput

0.536

High

163418

MAGA9
Melanoma-associated antigen 9

1

5

High-throughput

0.536

High

163419

SOX2
Transcription factor SOX-2

1

13

High-throughput

0.536

High

163423

ACTB
Actin, cytoplasmic 1

1

2

High-throughput

0.536

High

163437

TOM34
Mitochondrial import receptor subunit TOM34

1

3

High-throughput

0.536

High

163450

TSH1
Teashirt homolog 1

1

7

High-throughput

0.536

High

163464

SCYL1
N-terminal kinase-like protein

1

2

High-throughput

0.536

High

163476

M3K20
Mitogen-activated protein kinase kinase kinase 20

1

4

High-throughput

0.536

High

163474

ARNT2
Aryl hydrocarbon receptor nuclear translocator 2

1

0

High-throughput

0.518

High

163435

FA50A
Protein FAM50A

1

0

High-throughput

0.513

High

163451

HDGR2
Hepatoma-derived growth factor-related protein 2

1

0

High-throughput

0.513

High

163458

CMTR1
Cap-specific mRNA

1

0

High-throughput

0.513

High

163431

SQSTM
Sequestosome-1

1

0

Small-scale

0.505

High

163405

A4
Amyloid-beta precursor protein

1

3

High-throughput

0.501

High

163410

DRD1
D(1A) dopamine receptor

1

1

Small-scale

0.501

High

163434

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

1

High-throughput

0.494

High

163427

EPS8
Epidermal growth factor receptor kinase substrate 8

1

1

High-throughput

0.489

High

163446

MPP7
MAGUK p55 subfamily member 7

1

1

High-throughput

0.489

High

163452

LIPB1
Liprin-beta-1

1

3

High-throughput

0.489

High

163477

TMOD3
Tropomodulin-3

1

3

High-throughput

0.489

High

163479

AT7L1
Ataxin-7-like protein 1

1

1

High-throughput

0.489

High

163404

ANXA1
Annexin A1

1

1

High-throughput

0.481

High

163433

DGCR6
Protein DGCR6

1

1

High-throughput

0.481

High

163403

BRD4
Bromodomain-containing protein 4

1

5

High-throughput

0.479

High

163406

SP1
Transcription factor Sp1

1

5

Small-scale

0.479

High

163426

NFIA
Nuclear factor 1 A-type

1

8

High-throughput

0.479

High

163466

TBX5
T-box transcription factor TBX5

1

14

High-throughput

0.479

High

163447

Q5TZZ9
Annexin

1

1

High-throughput

0.470

High

163414

BMI1
Polycomb complex protein BMI-1

1

4

High-throughput

0.445

High

163483

X5DP20
DiGeorge syndrome critical region 6 isoform D

1

1

High-throughput

0.417

High

163480

PIGL
N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase

3

0

High-throughput

0.347

High

163478

OSGI1
Oxidative stress-induced growth inhibitor 1

2

0

High-throughput

0.327

High

163408

NDUB7
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7

2

0

High-throughput

0.316

High

163411

IBP6
Insulin-like growth factor-binding protein 6

2

0

High-throughput

0.316

High

163421

MCCD1
Mitochondrial coiled-coil domain protein 1

2

0

High-throughput

0.316

High

163422

KR108
Keratin-associated protein 10-8

2

0

High-throughput

0.316

High

163424

CTG1B
Cancer/testis antigen 1

2

0

High-throughput

0.316

High

163440

KR192
Keratin-associated protein 19-2

2

0

High-throughput

0.316

High

163441

KRA61
Keratin-associated protein 6-1

2

0

High-throughput

0.316

High

163442

KRA62
Keratin-associated protein 6-2

2

0

High-throughput

0.316

High

163444

KR196
Keratin-associated protein 19-6

2

0

High-throughput

0.316

High

163454

KR111
Keratin-associated protein 11-1

2

0

High-throughput

0.316

High

163460

F168A
Protein FAM168A

2

0

High-throughput

0.316

High

163469

ANKMT
Adenine nucleotide translocase lysine N-methyltransferase

2

0

High-throughput

0.316

High

163475

BPIA1
BPI fold-containing family A member 1

2

0

High-throughput

0.316

High

163482

T10B
Mitochondrial import inner membrane translocase subunit Tim10 B

2

0

High-throughput

0.316

High

163449

CA094
Uncharacterized protein C1orf94

1

0

High-throughput

0.299

High

163412

AMRP
Alpha-2-macroglobulin receptor-associated protein

1

0

High-throughput

0.279

Low

163455

RIOX2
Ribosomal oxygenase 2

1

0

High-throughput

0.279

Low

47285

A0A6Q8PF08
Peripheral myelin protein 22

1

0

High-throughput

0.268

Low

163443

KRA63
Keratin-associated protein 6-3

1

0

High-throughput

0.268

Low

163445

KR221
Keratin-associated protein 22-1

1

0

High-throughput

0.251

Low

163453

KR131
Keratin-associated protein 13-1

1

0

High-throughput

0.251

Low

163473

GBB4
Guanine nucleotide-binding protein subunit beta-4

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025