HitPredict

Interactor 1: RPC2 (P22276)
DNA-directed RNA polymerase III subunit RPC2 (RNA polymerase III subunit C2) (EC 2.7.7.6) (C128) (DNA-directed RNA polymerase III 130 kDa polypeptide)
Gene: RET1

Interactor 2: RPC2 (P22276)
DNA-directed RNA polymerase III subunit RPC2 (RNA polymerase III subunit C2) (EC 2.7.7.6) (C128) (DNA-directed RNA polymerase III 130 kDa polypeptide)
Gene: RET1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

The method score is based on:

Property	Details
Experiments	30593915
Identification Methods	affinity chromatography technology
Interaction Type	physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	RNA_pol_Rpb2_1~RNA_pol_Rpb2_1, RNA_pol_Rpb2_1~RNA_pol_Rpb2_3, RNA_pol_Rpb2_1~RNA_pol_Rpb2_4, RNA_pol_Rpb2_1~RNA_pol_Rpb2_5, RNA_pol_Rpb2_1~RNA_pol_Rpb2_6, RNA_pol_Rpb2_2~RNA_pol_Rpb2_2, RNA_pol_Rpb2_3~RNA_pol_Rpb2_4, RNA_pol_Rpb2_3~RNA_pol_Rpb2_5, RNA_pol_Rpb2_3~RNA_pol_Rpb2_6, RNA_pol_Rpb2_4~RNA_pol_Rpb2_5, RNA_pol_Rpb2_5~RNA_pol_Rpb2_6, RNA_pol_Rpb2_6~RNA_pol_Rpb2_6, RNA_pol_Rpb2_6~RNA_pol_Rpb2_7
Common GO terms	GO:0003677 - DNA binding GO:0003899 - DNA-directed RNA polymerase activity GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005666 - RNA polymerase III complex and 7 others more... GO:0005739 - mitochondrion GO:0006383 - transcription by RNA polymerase III GO:0006384 - transcription initiation at RNA polymerase III promoter GO:0006386 - termination of RNA polymerase III transcription GO:0008270 - zinc ion binding GO:0032549 - ribonucleoside binding GO:0042797 - tRNA transcription by RNA polymerase III
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1	1149
Sc

1	1149

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Last updated: 11Aug2025