HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: PKHM3 (Q6ZWE6)
Pleckstrin homology domain-containing family M member 3 (PH domain-containing family M member 3) (Differentiation associated protein)
Gene: PLEKHM3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.650

Property	Details
Experiments	33961781, 36931259, 28514442
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 245 Hs			1 761
+	Hs
		909720 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		PKHM3_HUMAN (1-761): 0: 1280: 100.00
+	Hs
		927202 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		PKHM3_HUMAN (1-761): 0: 1280: 100.00
+	Hs
		683477 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		PKHM3_HUMAN (1-761): 0: 1280: 100.00
+	Hs
		982182 1433F_HUMAN (2-242): 7.16e-106: 307: 71.43		PKHM3_HUMAN (1-761): 0: 1280: 100.00
+	Hs
		904755 1433G_HUMAN (1-242): 5.48e-105: 305: 70.33		PKHM3_HUMAN (1-761): 0: 1280: 100.00
+	Hs
		909874 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		RUBIC_HUMAN (472-733): 2.2e-105: 346: 32.58
+	Hs
		927365 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		RUBIC_HUMAN (472-733): 2.2e-105: 346: 32.58
+	Hs
		683591 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		RUBIC_HUMAN (472-733): 2.2e-105: 346: 32.58
+	Hs
		982350 1433F_HUMAN (2-242): 7.16e-106: 307: 71.43		RUBIC_HUMAN (472-733): 2.2e-105: 346: 32.58
+	Hs
		904938 1433G_HUMAN (1-242): 5.48e-105: 305: 70.33		RUBIC_HUMAN (472-733): 2.2e-105: 346: 32.58