HitPredict

Interactor 1: ENPP1 (P22413)
Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (E-NPP 1) (Alkaline phosphodiesterase I) (EC 3.1.4.1) (Membrane component chromosome 6 surface marker 1) (Nucleotide diphosphatase) (Nucleotide pyrophosphatase) (NPPase) (EC 3.6.1.9) (Phosphodiesterase I/nucleotide pyrophosphatase 1) (Plasma-cell membrane glycoprotein PC-1) [Cleaved into: Ectonucleotide pyrophosphatase/phosphodiesterase family member 1, secreted form]
Gene: ENPP1

Interactor 2: CALX (P27824)
Calnexin (IP90) (Major histocompatibility complex class I antigen-binding protein p88) (p90)
Gene: CANX

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005509 - calcium ion binding GO:0016020 - membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 925 Hs			1 592
+	Hs
		170659 ENPP1_HUMAN (1-925): 0: 1364: 100.00		CLGN_HUMAN (11-546): 0: 652: 59.85
+	Hs
		648307 ENPP1_HUMAN (1-925): 0: 1364: 100.00		CALR3_HUMAN (64-470): 4.24e-135: 400: 26.59
+	Hs
		699314 ENPP4_HUMAN (209-598): 1.79e-146: 443: 37.76		CALX_HUMAN (1-592): 0: 786: 100.00
+	Hs
		171046 ENPP4_HUMAN (209-598): 1.79e-146: 443: 37.76		CLGN_HUMAN (11-546): 0: 652: 59.85
+	Hs
		698733 PIGG_HUMAN (188-433): 1.41e-49: 192: 19.08		CALX_HUMAN (1-592): 0: 786: 100.00
+	Hs
		170596 PIGN_HUMAN (200-447): 7.35e-55: 208: 15.73		CLGN_HUMAN (11-546): 0: 652: 59.85
+	Hs
		170890 PIGO_HUMAN (211-433): 2.48e-50: 194: 15.35		CLGN_HUMAN (11-546): 0: 652: 59.85
+	Hs
		170792 PIGG_HUMAN (188-433): 1.41e-49: 192: 19.08		CLGN_HUMAN (11-546): 0: 652: 59.85