Interactor 1: RFA1 (P27694)
Replication protein A 70 kDa DNA-binding subunit (RP-A p70) (Replication factor A protein 1) (RF-A protein 1) (Single-stranded DNA-binding protein) [Cleaved into: Replication protein A 70 kDa DNA-binding subunit, N-terminally processed]
Gene: RPA1

Interactor 2: BLM (P54132)
RecQ-like DNA helicase BLM (EC 5.6.2.4) (Bloom syndrome protein) (DNA 3'-5' helicase BLM) (DNA helicase, RecQ-like type 2) (RecQ2) (RecQ protein-like 3)
Gene: BLM

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 0.60 0.756

The method score is based on:

Property Details
Experiments 25135477, 10825162, 12181313, 30279242, 12724401, 24239288, 26474068, 24126761, 37827155, 24332808, 15775963, 15965237
Identification Methods affinity chromatography technology, pull down, enzymatic study, proximity labelling technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, enzyme linked immunosorbent assay, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000723 - telomere maintenance
GO:0000724 - double-strand break repair via homologous recombination
GO:0003697 - single-stranded DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 5 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 616
Hs

1 1417
+ Hs
+ Hs
+ Xl
+ Hs
+ Hs
+ Hs
+ Sp
+ Sc
+ Hs
+ Ce
+ Hs

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Last updated: 15 Jul 2024